Can boosting tumor blood flow make cancer treatments work better?
NCT ID NCT01455363
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether temporarily blocking and then releasing blood flow to a skin cancer (basal cell carcinoma) could increase blood flow to the tumor. Twelve adults with this type of skin cancer had their tumor's blood supply briefly clamped during surgery, and blood flow was measured with a special laser camera. The goal was to see if this technique could later be used to improve oxygen levels in tumors, potentially making treatments like radiation or chemotherapy more effective.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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12 people
The number who actually took part.
- Start date
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Jun 2011
- Finished
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Oct 2011
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 18 * Histologically proved cutaneous BCC * Patient being informed and having signed the consent to participate to the study Exclusion Criteria: * Counter-indication to surgery * Patient being unable to attend future follow-up visits * Patient with severe cognitive impairment * Patient not affiliated to a social security regimen * Patient with limb BCC and history of peripheral vascular artery surgery like bypass and/or vascular prothesis on the same limb (tourniquet counter-indication) * Local bone invasion of BCC detected with imagery
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Institut Curie
Paris, 75005, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.