Emory University

This study looked at how healthy adults' immune systems respond to the oral cholera vaccine Vaxchora. Researchers measured antibodies and other immune cells in the blood to see how well the vaccine works. The goal is to better understand protection against cholera, a severe diarr…

This early-phase trial tested a combination of two drugs—pembrolizumab (an immunotherapy) and XL888 (a targeted therapy)—in 47 people with advanced gastrointestinal cancers that had spread or couldn't be removed. The main goal was to find the safest dose and check for side effect…

This study looked at whether adding citrate to the fluid used during dialysis can slow the buildup of calcium in the arteries of people with kidney failure. Fifty-four adults on hemodialysis who already had some artery calcification took part. Each person used both a standard dia…

This study tested a program that brings together diabetes care, continuous glucose monitoring, and support for social needs like food and housing. It involved 65 adults with type 2 diabetes and high blood sugar levels. The goal was to see if this approach helps patients manage th…

This early study tested whether combining an immunotherapy drug (pembrolizumab) with precise radiation (stereotactic radiosurgery) is safe for people with melanoma or lung cancer that has spread to the brain. 25 participants received the combination. The main goal was to check fo…

This study tested whether an automated insulin delivery (AID) system works better than standard insulin shots for managing blood sugar in hospitalized adults with type 1 or type 2 diabetes. 130 patients on general medical or surgical floors were randomly assigned to use either th…

This study tested a mobile app called UrApp to help families manage childhood nephrotic syndrome, a chronic kidney disease. About 58 caregivers of children with the condition used the app or received standard care for one year. The goal was to see if the app improved medication a…

This study tested a program to help low-income smokers quit by making their homes and cars smoke-free. 918 adults received mailings and coaching calls to support creating these bans. The goal was to see if this approach leads to lasting smoking cessation, verified by saliva tests…

This early study tested whether giving focused radiation to brain tumors before surgically removing them is safe and might lower the chance of the cancer coming back. 26 adults with cancer that spread to the brain took part. The main goal was to see how many had serious side effe…

This study tested whether giving pregnant women in India, Guatemala, Peru, and Rwanda cleaner-burning LPG stoves (instead of smoky biomass fuels) leads to healthier babies. About 3,200 households took part, with half receiving the stoves and fuel. Researchers tracked birth weight…

This study tested whether a smartphone app and phone calls could help people with heart disease do rehab at home instead of going to a clinic. 258 veterans took part. The goal was to see if this approach improved their ability to exercise, helped them stick with the program, and …

This study followed 240 young men who have sex with men for two years to help them stay on HIV PrEP and prevent sexually transmitted infections. Participants used a smartphone app to track risks and received counseling to avoid stopping PrEP early. The goal was to improve HIV and…

This study tested whether a drug called GM-CSF can improve symptoms and blood flow in people with peripheral artery disease (PAD), a condition where leg arteries narrow, causing pain and limiting walking. 151 adults with stable PAD received either GM-CSF or a placebo in two 3-wee…

This study tested whether having a personal pain coach helps people recover from orthopedic surgery for sports injuries. 148 patients were assigned to work with a Life Care Specialist in person or via telehealth, or to receive standard written instructions. The coaches taught min…

This pilot study tested a new word game-based workbook to help people with diabetes learn how to manage their condition. 25 participants completed the workbook during clinic visits or at home, playing games that taught diabetes terms and meal planning. The goal was to see if this…

This study tested a painless brain stimulation treatment called tDCS in 38 veterans with chronic pain, PTSD, and depression. The treatment uses low-level electrical currents to calm overactive pain and stress circuits in the brain. Researchers wanted to see if adding tDCS to stan…

This study tested a mind-body training program called I-STRONG for teenagers with sickle cell disease who have chronic pain. The program combines gentle movement and mental exercises to help reduce pain and improve daily life. Researchers worked with 45 teens to see if the progra…

This study tested the drug Trikafta in 32 adults with non-cystic fibrosis bronchiectasis, a lung condition that causes coughing and breathing problems. Participants took Trikafta for four weeks, and researchers measured changes in lung function, quality of life, and weight. The g…

This study looked at whether a steroid injection could improve asthma control in children who have frequent asthma attacks. 68 children aged 6 to 21 received the injection and were monitored for 48 weeks. The main goal was to see if their asthma symptoms got better two weeks afte…

This study looked at whether a program to offer family planning to women right after giving birth could work on a large scale in Rwanda. Over 42,000 people took part, including clinic directors, nurses, and community health workers. The goal was to train staff and provide counsel…

This study tested a program called Keeping on Course for people with mild cognitive impairment (MCI) and their care partners. The goal was to teach communication skills to help them feel more in control while coping with MCI. 29 dyads participated in the program, which was delive…

This study looked at over 2,000 adults with sepsis in emergency rooms. Researchers used an algorithm based on vital signs to identify patients who might do better with balanced fluids instead of normal saline. The goal was to see if prompting doctors to use balanced fluids could …

This study tested whether peer recovery coaches—people with lived experience—can help emergency department patients with substance use disorders connect to treatment and support. 144 adults were split into three groups: in-person coaching, video call coaching, or just a list of r…

This study looked at whether a non-invasive brain stimulation technique called TMS can improve PTSD symptoms and change related brain activity and stress responses. Researchers worked with 63 adults who had partial PTSD to see if the treatment was feasible and effective. The goal…

This study looked at 160 adults having surgery on their upper arm, elbow, wrist, or hand. It compared different types of stitches and stitching methods to see which ones cause less pain and help wounds heal better. The goal was to find the best way to close surgical cuts to impro…

This study looked at how fast treadmill walking, with or without mild electrical stimulation, helps people who have had a stroke improve their walking. Fifty-five stroke survivors took part to help researchers understand why these treatments work and who benefits most. The goal i…

This study tested an online group program designed to help young Black men living with HIV feel more connected and improve their health. Sixty participants took part in the program, which was adapted from an in-person version for online delivery. The goal was to see if the progra…

This study looked at whether taking statins (cholesterol-lowering drugs) changes how well the flu vaccine works. Researchers measured antibody levels in the blood and checked gut bacteria from stool samples in 63 adults aged 18-50. The goal was to understand how statins affect lo…

This study looked at how adults' immune systems respond to the live attenuated flu vaccine (nasal spray). The goal was to understand why this vaccine is less effective in adults than in children. By analyzing blood samples from 51 participants, researchers hope to design better f…

This study tested a computer program that sorts sepsis patients into four groups based on their vital signs in the first 8 hours. The goal is to see if these groups have different outcomes, which could help design better treatments in the future. Over 1,900 adults participated, b…

This study tested tiny particles with microneedles (STAR particles) on the skin of 20 healthy adults. The goal was to find the best way to apply them to create small punctures that could help future topical medications work better. No active drugs were used. The study measured sk…

This study tested two ways to help infants at risk for autism: teaching parents about early social communication milestones and providing either parent-led or clinician-led therapy for babies showing early signs. About 269 families with a high-risk infant (who has an older siblin…