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Steroid shot may ease asthma in kids with frequent attacks

NCT ID NCT04002362

Symptom relief Sponsor: Emory University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how a steroid injection (triamcinolone acetonide) affects asthma symptoms in children aged 6 to 21 who have frequent flare-ups. 68 participants received the shot and were followed for 48 weeks. The main goal was to see if symptoms improved two weeks after the injection and how stable those improvements were over time.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

68 people

The number who actually took part.

Started

Nov 2019

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

6 to 21 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 6 to less than 21 years at the enrollment visit * Physician diagnosis of asthma * History of an asthma exacerbation in the previous 12 months, defined as either: * Treatment with systemic corticosteroids, or * Increase in rescue medication use (i.e., albuterol or inhaled corticosteroid) for 24 hours or more, or * One or more missed school days due to asthma symptoms, or * An unscheduled visit for asthma at either a physician's office, urgent care, hospital emergency room, or * Hospitalization for asthma Exclusion Criteria: * Previous allergic reaction to systemic corticosteroids * Hepatic, biliary, or renal disease that can interfere with drug metabolism/excretion * Chronic medical disorders that may increase the risk of drug-related injury, including osteogenesis imperfecta (increased risk of fracture with corticosteroids), or Crohn's disease, ulcerative colitis, juvenile rheumatoid arthritis, clotting disorders, or Factor deficiency (increased risk of bleeding with corticosteroid therapy) * Pregnancy * Current smoking * Congenital disorders or deformities of the chest wall, lungs or airways * History of premature birth \<35 weeks gestation * Unwillingness to receive triamcinolone * Planning to relocate before study completion

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Conditions

The condition(s) this trial relates to.

asthma childhood onset asthma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Asthma in children

Contacts and locations

Locations

  • Children's Healthcare of Altanta

    Atlanta, Georgia, 30322, United States

  • Emory Children's Center

    Atlanta, Georgia, 30322, United States

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