ASTHMA IN CHILDREN

This study tests a program called PRAGMATIC-S that connects doctors' offices with schools to help children with asthma get better care. About 420 children aged 4 to 12 with persistent or uncontrolled asthma will take part. The goal is to improve asthma control and quality of life…

This study tests whether a daily soluble fiber drink (inulin) can improve asthma control in children ages 6-17. Researchers will measure gut bacteria, nasal inflammation, and asthma symptoms over 4-6 weeks. The goal is to see if changing diet can help manage asthma, not cure it.

This study tests whether a smartphone app and digital sensors can help families better manage their child's asthma. About 80 parent-child pairs will either get the app with extra support from an asthma coordinator or just the app alone. The goal is to see if this approach is prac…

This study tests whether using simple cockroach bait in the home can reduce asthma symptoms in children. Researchers will enroll 290 children aged 5-17 with asthma who live in the New Orleans area and have cockroach exposure. The goal is to see if targeting this single allergen i…

This study tests two school-based programs to help children aged 5-12 from low-income communities in Colorado better control their asthma. The goal is to reduce asthma attacks and missed school days by having school nurses and asthma navigators coordinate care with doctors and co…

This study tests whether a soy supplement (isoflavones) can reduce asthma risk in infants who have a genetic tendency to produce more of an inflammatory protein. 65 babies at high risk for asthma will receive either soy isoflavones or a placebo mixed into food twice daily for 7 m…

This study tests a program called TEACH-ER that helps children with asthma after they leave the emergency room. It includes asthma education, a virtual doctor visit within a week, and follow-up video calls to help families manage asthma at home. The goal is to see if this support…

This study tests a program called CHAMPION that helps overweight children with asthma manage their weight and breathing. Researchers want to see if doing the program online works as well as meeting in person. About 500 children aged 4 to 17 with asthma and a BMI in the 85th perce…

This study tests whether extra support from an asthma navigator after a child's hospital stay can reduce asthma-related readmissions. About 340 children aged 4-12 and their caregivers will be randomly assigned to standard care or standard care plus navigator support. The study fo…

This study looks at whether school-based health centers can improve asthma care for children in underserved communities. About 400 children with uncontrolled asthma will receive guideline-based assessments, preventive medication, and directly observed therapy at school. The goal …

This study looks at whether two simple, non-invasive tests—a breath test (FeNO) and a blood test (eosinophil count)—can accurately diagnose asthma in children aged 6 to 17. Currently, diagnosing asthma often requires a hospital-based breathing challenge test that is hard to acces…

This study looks at whether measuring inflammation in the breath and blood can help prioritize who gets asthma tests first. About 1,500 people aged 6 and older with suspected asthma will take a simple breath test and a blood test before their regular lung function tests. The goal…

This study tests whether a smartphone app can help parents reduce their young children's exposure to second-hand smoke. About 160 children under 6 who live with a smoking parent will take part. The goal is to lower the children's urine cotinine levels, a marker of smoke exposure,…

This study tests whether a questionnaire that measures how confident teens feel about managing their asthma can help doctors give better support. About 98 teenagers aged 12-18 with asthma will either get this tailored approach or a standard check-up. After three months, researche…

This study tests whether a short-term therapy for depression, called Enhanced IPT-B, can help Black mothers of children with asthma feel better and possibly improve their child's asthma. About 60 mothers will receive either the therapy or standard care plus extra support. The goa…

This study looks at how sleep length impacts the immune system and lung function in urban children with asthma. Researchers will test 204 kids aged 7-11 by changing their sleep and measuring immune markers. The goal is to understand why city kids with asthma often have worse symp…

This study is testing a wearable stethoscope patch that listens to breath sounds in children with asthma. The goal is to see if the device can detect wheezing early, helping doctors manage asthma attacks. About 10 children hospitalized for asthma will wear the patch for up to 8 h…

This study looks at whether giving doctors extra support through their electronic health records can increase the use of a preferred asthma treatment called SMART for children with moderate to severe asthma. The researchers will track how often doctors start and continue SMART th…

This study looks at ways to help doctors prescribe a treatment called SMART for children with moderate to severe asthma. SMART uses one inhaler for both daily control and quick relief. The study will test if extra support like community health workers helps more kids get this tre…

This study looks at how well hospitals follow the latest GINA 2025 guidelines when treating children (ages 6-17) having an asthma attack. Researchers will check if using these guidelines leads to better diagnosis, treatment, and follow-up care. The goal is to improve care for chi…

This study looks at how certain medicines act in the bodies of children and young adults under 21. Researchers want to find the safest and most effective doses for these age groups. Participants are already receiving these drugs as part of their normal care. No new treatments are…

This study looks at whether a new, step-by-step care plan for children having mild to moderate asthma attacks can improve how quickly they get the right treatment. The plan is designed to help doctors and nurses work together better. About 249 children and their healthcare provid…

This study looks at the bacteria living in the airways of infants under 2 years old with severe asthma. Researchers want to understand how these bacteria differ from normal and how they relate to the immune system. The goal is to find new ways to treat severe asthma in babies. Th…