Emory University

This study tests whether combining two drugs, vidutolimod and nivolumab, can help the immune system find and destroy prostate cancer cells that have spread. It is for men whose cancer has stopped responding to standard hormone therapy and chemotherapy. The goal is to see if this …

This study tests two drugs, pembrolizumab and cabozantinib, in 36 people with head and neck cancer that has returned or spread and cannot be surgically removed. The goal is to see if the combination shrinks tumors and delays cancer growth. Participants receive both drugs intraven…

This study tests whether giving two drugs—lenvatinib and pembrolizumab—before surgery can shrink tumors in people with advanced kidney cancer that hasn't spread to other organs. About 18 participants will receive the combination for 12 weeks, then have surgery. The main goal is t…

This study looks at whether using a blood test to measure certain proteins (biomarkers) can help doctors create a more personalized treatment plan for people with coronary artery disease. About 276 adults with stable heart disease will be split into two groups: one gets treatment…

This study tests whether giving the drug cabozantinib before surgery can shrink tumors in people with locally advanced kidney cancer. About 22 participants will receive the drug for a short time before their operation. The goal is to see if this approach helps control the disease…

This study tests whether giving the immunotherapy drug atezolizumab before surgery can help treat HPV-related throat cancer that can be removed. About 20 adults with stage I oropharyngeal cancer will receive two doses of atezolizumab before their planned surgery. Researchers will…

This study looks at whether people with type 2 diabetes can safely keep taking their usual diabetes pills while in the hospital, instead of switching to insulin. About 255 adults aged 18-80 who are admitted to general medical or surgical units will take part. The goal is to see i…

This early-phase study tests the safety and best dose of two drugs, venetoclax and tocilizumab, in people with a specific genetic subtype of multiple myeloma (t(11;14)) that has returned or stopped responding to treatment. The trial includes both African American and non-African …

This early-phase study tests whether adding an experimental drug (VX15/2503) to standard immunotherapy (ipilimumab or nivolumab) helps the immune system attack stage III melanoma before surgery. About 41 adults with resectable melanoma will receive different combinations of these…

This study tests whether adding abatacept to standard medications can prevent graft-versus-host disease (GVHD) in 30 children and teens receiving stem cell transplants from unrelated donors for serious blood disorders. GVHD is a dangerous complication where donor cells attack the…

This study tests whether combining two drugs—niraparib and panitumumab—can help control advanced colorectal cancer that has spread. The trial includes 26 adults whose cancer did not respond to prior treatment. The goal is to see if the combination shrinks tumors or keeps them sta…

This study tests a combination of three drugs (docetaxel, ramucirumab, and pembrolizumab) in 30 people with advanced non-small cell lung cancer that worsened after standard chemotherapy and immunotherapy. The goal is to see if this triple therapy is safe and works better than cur…

This study tests whether adding furosemide (a diuretic or "water pill") to a special PET/CT scan can reduce bladder radioactivity and improve detection of recurrent prostate cancer in 20 men whose PSA levels rose after prostate removal. Participants receive two scans—one with and…

This early trial tests a new imaging method called qOBM that may help brain surgeons see tumor edges more clearly during surgery. About 24 adults with certain brain tumors (glioblastoma, astrocytoma, or oligodendroglioma) will be enrolled. The goal is to check if the device is sa…

This study tests whether a low-sugar diet can prevent non-alcoholic fatty liver disease (NAFLD) in Hispanic children aged 6 to 9 who are at higher risk. Over 2 years, 103 kids will either follow the diet or eat as usual. Researchers will measure liver fat and inflammation to see …

This study tests whether giving expectant parents clear, factual vaccine information during pregnancy can increase their confidence in vaccines and lead to timely shots for both mom and baby. About 770 first-time parents with a single pregnancy will take part. The goal is to see …

This study tests a program to help more HIV-positive adults get the HPV vaccine, which can prevent HPV-related cancers. People with HIV are at much higher risk for these cancers. The program gives clinics and doctors tools and training to encourage vaccination. The study will enr…

This study tests whether a smartphone game can help prevent HIV in young people aged 12-17 in Kenya. About 1000 teens and 500 parents will play the game, which teaches about safe sex, condom use, and avoiding risks. The goal is to see if the game helps teens delay sex and use pro…

This pilot study tests a 12-month lifestyle program designed to lower stress and improve memory in 45 adults aged 50+ with mild cognitive impairment (MCI). Participants join group and individual activities focused on nutrition, exercise, and brain health. The study checks if the …

This early-stage study looks at whether giving testosterone to men with low levels before and after major urologic surgery is safe and can improve recovery. Researchers will track quality of life, frailty, complications, and hospital stay length. The goal is to see if this approa…

This study tests whether a single dose of MDMA, given during a 10-day intensive therapy program, can help ease PTSD symptoms. Forty adults with PTSD will receive the combination treatment at Emory University. The goal is to see if MDMA makes the therapy work better and faster.

This study in rural Guatemala looks at how burning plastic waste affects people's health. About 400 women of childbearing age from 16 villages will take part. Half the villages will join weekly group sessions to learn ways to reduce plastic burning, while the other half will not.…

This study is testing a program called CHIMES to help young Black gay, bisexual, and other men who have sex with men (ages 18-29) who are living with HIV get better access to both HIV care and mental health support. The program will be offered at two clinics in Atlanta. Researche…

This study looks at how the RSV vaccine affects the immune system in adults aged 60 and older. Researchers will measure antibodies and other immune markers in 14 volunteers over six months. The goal is to understand why the vaccine works and find early signs of a strong immune re…

This study looks at whether a tailored asthma navigator program can help children aged 5 to 16 who were in the pediatric ICU for asthma. Researchers will identify factors affecting asthma self-management and test the program's effectiveness at hospital discharge. The goal is to r…

This study looks at immune cells from people with autoimmune diseases, infectious diseases, and healthy volunteers. Researchers want to understand how these cells differ. The goal is to learn more about how the immune system works in different conditions. Up to 2,500 people will …

This early-phase trial studies how two oral drugs, defactinib and VS-6766, reach glioblastoma tumors in the brain. Fourteen patients with new or recurrent glioblastoma will receive a single dose before surgery, and drug levels will be measured in tumor tissue and blood. The goal …