Centre Hospitalier Universitaire De Nice

This study tested whether injecting a clot-dissolving drug directly into the brain's fluid spaces could reduce deaths in people with severe bleeding after a brain aneurysm rupture. Nineteen participants received the treatment, and researchers tracked how many were alive after 30 …

This pilot study tested the diabetes drug metformin in 20 adults with advanced melanoma that had spread and was no longer curable by surgery. The goal was to see if metformin could shrink tumors or slow the disease. The study is complete, and results will show if this common, low…

This study tested whether starting treatment early in vitiligo can stop the immune system from attacking skin cells and improve repigmentation. 51 adults with different stages of vitiligo received a combination of light therapy (narrowband UVB) and low-dose steroid pills for 6 mo…

This study tested whether low doses of IL2, a protein that helps regulate the immune system, could treat severe alopecia areata (patchy hair loss). 44 adults with at least 50% scalp hair loss that did not respond to standard treatments received either IL2 or a placebo. The goal w…

This study tested a gel called Picato (ingenol mebutate) on 20 people with a very early form of skin cancer called lentigo maligna on the face. Participants either could not have surgery or chose not to. The gel was applied to the skin to see if it could make the cancer go away. …

This study tested whether tranexamic acid, a drug used to reduce bleeding, can prevent dark spots that often appear after skin inflammation. Ten healthy men with darker skin tones received the drug and had small blisters created on their skin to mimic injury. The goal was to see …

This study tested whether a connected knee brace, combined with an online physiotherapist, could improve muscle strength and reduce knee pain in people with knee osteoarthritis. 65 adults aged 50-80 who could walk without help and use a smartphone took part. The goal was to see i…

This study looked at whether hypnosis can reduce chronic itching that has no known cause. Twelve adults with this condition took part. The goal was to see if hypnosis, which helps with pain, could also ease itching. Results may offer a drug-free way to manage symptoms.

This study looked at whether a type of muscle strengthening called eccentric exercise can improve walking in people with knee osteoarthritis. Researchers compared it to standard concentric exercise in 40 adults aged 40-85. The main goal was to see how far participants could walk …

This study tested whether injecting etanercept directly into inflamed joints (knee, wrist, ankle, elbow) can safely ease pain in people with rheumatoid arthritis. 34 adults with at least 6 months of RA and a painful flare lasting 2 weeks or more took part. The goal was to compare…

This study aims to create a detailed map of the cells lining the airways in healthy people. By analyzing gene activity in individual cells from different parts of the respiratory tract, researchers hope to better understand how chronic lung diseases develop. Fifteen healthy, non-…

This study looked at why vitiligo repigmentation varies by body location. Researchers compared skin samples from 20 people with and without vitiligo to understand what factors in the skin might block repigmentation in hard-to-treat areas like hands and feet. The goal was to gathe…

This pilot study looked at 20 adults with acute myeloid leukemia (AML) who cannot have strong chemotherapy. Researchers measured the amount of the drug venetoclax in the blood to see if it relates to how well the drug works and its side effects. The goal is to learn if personaliz…

This study looked at 150 adults with spine injuries to see if adding an emergency MRI to a standard CT scan changes how doctors treat them. The goal was to find fractures that only show up on MRI and see if that alters the treatment plan. Results will help decide if emergency MRI…

This study used a computer model (digital twin) of one patient's upper jaw to compare three different dental implant arrangements for immediate tooth replacement after bone grafting. The goal was to see which setup spreads biting forces most safely. The all-on-six configuration (…

This study looked at 40 adults having laparoscopic bowel surgery to see if adding diluted epinephrine to a numbing medicine (ropivacaine) used in a TAP block (a type of pain shot) lowers the peak amount of the medicine that enters the blood. The goal is to improve safety by reduc…

This study looked at how apathy (lack of interest or motivation) influences different types of fatigue in older adults with mild neurocognitive disorders. Researchers compared 30 apathetic and 30 non-apathetic participants aged 65-85. Participants wore activity trackers for a wee…

This study looked at two different ways of giving the antibiotic cloxacillin to 12 people with bone and joint infections caused by Staphylococcus aureus bacteria. The goal was to see if giving the drug continuously or in short bursts worked equally well. Researchers measured drug…

This study looked at 38 adults getting a liver transplant to see if a failing liver makes less of a natural substance called pyrophosphate, which prevents calcium buildup in blood vessels. Researchers measured pyrophosphate levels before and after the transplant. The goal was to …

This study looked at how the immune system responds to a harmless part of the cholera toxin when given through the mouth, nose, or under the tongue. It involved 40 healthy adults aged 18 to 50. The goal was to understand immune reactions better, which could help in designing futu…

This study tested whether LED light can speed up skin healing. Ten healthy adults had small laser spots on their forearms, then received LED treatment. Researchers measured skin color and water loss to see if LED helped recovery. The goal was to find the best LED settings for fut…