Centre Hospitalier Universitaire De Nice

This study tests whether amiloride, a drug usually used for high blood pressure, can reduce the number of migraine auras (visual or sensory disturbances that often come before the headache). About 40 adults with migraine with aura will take either amiloride or a placebo for a per…

This study is testing a new treatment called Zilucoplan in 55 French patients with myasthenia gravis, an autoimmune disease that causes muscle weakness. The goal is to see if the drug improves muscle strength and quality of life over three months, while also checking for side eff…

This study compares same-day discharge versus overnight hospital stay for people with uncomplicated appendicitis who have keyhole surgery. It aims to see if going home the same day is just as safe and leads to fewer complications within 30 days. About 1,400 participants aged 15-7…

This study compares two new pain management methods—methoxyflurane (an inhaled painkiller) and a virtual reality headset—against standard care for people with a dislocated shoulder. The goal is to see if these approaches can reduce the need for strong sedative drugs during the pr…

This study looks at whether adding a physical activity education program to adapted exercise helps people with mild or early major neurocognitive disorders (like early dementia). About 34 participants will be split into two groups: one doing only adapted physical activity, the ot…

This study tests whether Functional Proprioceptive Stimulation (FPS) helps people who recently had a stroke recover their balance and ability to move. About 32 participants will receive either active FPS or a sham (inactive) device during therapy sessions. The goal is to see if F…

This study tests whether wrapping a stitched finger nerve with a special skin scaffold (MatriDerm) helps improve sensation recovery. About 70 people with cut nerves in their fingers or palm will be randomly assigned to get either standard nerve stitching alone or stitching plus t…

This study looks at how certain natural chemicals in the body affect blood vessel health in people with pseudoxanthoma elasticum (PXE), a rare genetic disease that causes abnormal calcium buildup in tissues. Researchers will measure levels of these chemicals and enzymes in 45 adu…

This study looks at people with radiologically isolated syndrome (RIS) — early brain changes that may lead to multiple sclerosis — and compares them to people who have MS but no physical symptoms. Researchers want to see if digital tools, like smartphone tests, can detect subtle …

This study looks at 40 newborns with isolated rectal bleeding to see how many have a cow's milk protein allergy versus a temporary condition called transient neonatal colitis. Researchers will track whether bleeding stops when milk proteins are removed and returns when reintroduc…

This study checks if a classroom program called e-Bug, which teaches students about HPV, leads to more parents agreeing to the HPV vaccine. Researchers compared vaccination rates at one middle school that used the program with the rest of the region. No students were enrolled or …

This study looks at whether online health education workshops are practical and helpful for teenagers and young adults (ages 15-25) who have cancer. About 48 participants from across France will take part in three digital sessions designed to teach skills for managing daily life …