SUICIDAL IDEATION

This study aims to reduce suicidal thoughts and behaviors in people with PTSD. Researchers are testing whether adding a crisis response plan to standard prolonged exposure therapy works better than therapy alone. About 100 adults with PTSD and suicidal thoughts will participate, …

This study tests a program called TAILOR that helps teenagers with insomnia and suicidal thoughts improve their sleep. The goal is to see if fixing sleep problems can lower the risk of suicidal behavior. The study will involve 235 teens aged 11 to 18 who have had recent suicidal …

This study tests a 40-minute web-based program that teaches veterans coping skills for emotional distress linked to suicidal thoughts. Researchers will compare changes in suicidal thoughts and behaviors over one month between veterans who use the program and those receiving stand…

This study tests a mobile app called WellPATH-PREVENT for adults aged 50-90 who were recently hospitalized for suicidal thoughts or a suicide attempt. The app teaches skills to better manage emotions and aims to lower suicide risk. Researchers will measure changes in brain activi…

This study tests a new type of talk therapy that focuses on shame to help prevent suicide in teens aged 13-18 who are in a psychiatric hospital. About 42 teens will either get this shame-focused therapy or standard support. The goal is to see if the therapy is practical, acceptab…

This study tests a smartphone app called Jaspr Health for people who come to the emergency department with suicidal thoughts or recent suicide attempts. The app provides tools and support based on proven methods to help during the waiting time and beyond. Researchers will track 6…

This study is testing a new short-term treatment called Suicidal Crisis Intervention (SCI) to help adults who have attempted suicide or are in a suicidal crisis. The goal is to reduce suicidal thoughts and related feelings like hopelessness. About 390 participants will be randoml…

This study tests two mindfulness-based programs designed for Korean adolescents and young adults who have suicidal thoughts or self-harm behaviors. About 100 participants aged 15–30 will either join the program or receive usual care. Researchers will track changes in mood, sleep,…

This study tests a non-invasive brain stimulation technique called accelerated theta burst stimulation (aTBS) to see if it can reduce suicidal thoughts in people with treatment-resistant depression. Researchers will compare two types of stimulation (bilateral vs. unilateral) in 7…

This study tests a program called SUPERCEDE that helps veterans at risk for suicide get faster access to VA mental health services while they are receiving care from community doctors. About 100 veterans will be randomly assigned to either SUPERCEDE or a standard talk therapy. Th…

This early-phase study tests a non-invasive magnetic brain stimulation technique (iTBS) to see if it can safely reduce impulsivity and suicidal thoughts in veterans who have had a mild traumatic brain injury. About 55 veterans will receive daily sessions for two weeks. The goal i…

This study tests whether a single low dose of ketamine, given in the emergency department, is safe and practical for adults (ages 18-65) who are having serious suicidal thoughts. Researchers will monitor side effects and ask staff about their experience. The goal is to see if ket…

This study tests a digital program called I-CARE for teens aged 12-17 who are in the emergency room with suicidal thoughts or self-harm and waiting for a psychiatric bed. The program teaches coping skills through a tablet or phone, guided by a non-clinical helper. Researchers wan…

This study aims to reduce suicide among sexual and gender diverse young adults aged 18-24. It compares two brief suicide prevention programs adapted for this group, delivered via telehealth in primary care clinics. About 1,485 participants who screen positive for suicide risk but…

This study tests a smartphone app designed to help teenagers and young adults who have suicidal thoughts. The app lets teens and their doctors create a personalized safety plan and includes videos to teach coping skills and improve communication with parents. Researchers want to …

This study looks at how well a 20-week therapy called Dialectical Behavior Therapy for Adolescents (DBT-A) works for teens aged 13-18 who self-harm or have suicidal thoughts. Researchers will track self-harm episodes, suicide attempts, depressive symptoms, and quality of life rig…

This study tests whether a type of talk therapy, delivered via video call, can reduce suicidal thoughts and attempts in adults with physical disabilities (vision, hearing, or mobility issues). Researchers will enroll 60 people who have had recent suicidal thoughts or a recent sui…

This study tests whether an online recovery education and support program, led by trained teen peers and support specialists, can help teens aged 15-18 who were recently hospitalized for suicidal thoughts, depression, or anxiety. Participants are split into two groups: one gets t…

This study tests a smartphone-based sleep program (Sleepio) for teens ages 14-18 who have insomnia and were recently hospitalized for suicidal thoughts or behavior. The goal is to see if improving sleep can lower suicide risk. Participants will either receive the sleep program pl…

This study tests a non-invasive brain stimulation treatment called TMS for teens and young adults (ages 15-25) with depression and suicidal thoughts. The treatment is given over 5 days and uses MRI to guide targeting. Researchers want to see if it reduces depression and suicide r…

This study tests a new digital avatar (virtual coach) program for young adults aged 18-29 who visit the emergency department with alcohol misuse and suicidal thoughts. Participants are randomly assigned to use either the avatar program with supportive texts or a free suicide safe…

This study tests whether four ketamine infusions over two weeks can rapidly reduce suicidal thoughts in 36 adults with major depression. Participants will also have two MRI brain scans to see if changes in brain structure relate to symptom improvement. The goal is to find a fast-…

This study compares a new, lower-energy seizure therapy (LAP-ST) to standard electroconvulsive therapy (ECT) for quickly reducing suicidal thoughts in people with depression, bipolar disorder, or schizoaffective disorder. The goal is to see if the new treatment works as well or b…

This study tests whether adding a brief crisis coping strategy (Crisis Response Planning) to a standard PTSD talk therapy (Cognitive Processing Therapy) can lower suicidal thoughts and behaviors in veterans. About 190 active-duty service members and veterans with PTSD and recent …

This study tests if a 6-month therapy called Dynamic Deconstructive Psychotherapy (DDP) works better than standard care plus Brief Intervention and Contact (BIC) for reducing suicidal thoughts in teens and young adults ages 14 to 40. About 106 participants will be randomly assign…

This study tests whether deep transcranial magnetic stimulation (dTMS) is safe and helpful for teens aged 14-18 who are in the hospital for major depression. Sixty participants will receive either real or sham dTMS alongside their usual care. The goal is to see if dTMS can ease d…

This study tests whether morning light exposure can help regulate mood, improve sleep, and reduce suicidal thoughts in military personnel. Researchers will enroll 480 service members with mild depression or more. Participants will use a light device each morning to see if it impr…

This study looks at whether teaching teens (ages 12-17) who have suicidal thoughts how to use social media in active and helpful ways can reduce feelings of disconnection and distress. About 200 teens will take part in a brief educational program. The goal is to see if this appro…

This study looks at how different emotion regulation strategies—like distraction, seeking support, or thinking about reasons for living—affect suicidal thoughts in U.S. military personnel. Researchers will use smartphone surveys to track participants' strategies and feelings in r…

This study follows up to 10,000 medical students in Orleans, France, for up to 22 years to understand what leads to depression and other mental health problems. Researchers will compare students who enter medical school with those who don't, using yearly questionnaires. The goal …

This study looks at how the brain works differently in people who have attempted suicide versus those who have only thought about it. Researchers will also compare them to other psychiatric patients and healthy volunteers. Participants complete a one-time thinking and attention t…

This study works with 20 prison staff and 20 people in detention to improve three suicide prevention tools for use in jail settings. Through interviews, researchers will learn what works, what doesn't, and how to adapt these tools to the realities of prison life. The goal is to m…

This study tests an online training program for school counselors in Turkey to help them better prevent suicide among teenagers. About 60 counselors will take part, and researchers will measure if the training improves their knowledge, confidence, and attitudes toward suicide pre…

This study looks at how childhood trauma and stress might change tiny genetic molecules called microRNAs in the blood. Researchers hope these changes can help explain why some people develop depression or suicidal thoughts. 450 adults aged 18-60 with or without depression will gi…

This study tests a digital program called Flourish that aims to prevent suicide in teens who have been cyberbullied. About 20 middle and high school students will use the program for 12 weeks. Researchers want to see if schools can easily offer it and if it helps reduce distress …

This study tests a short therapy program (ASSIP-OA) designed to prevent suicide in adults aged 65 and older who have recently attempted suicide or had serious suicidal thoughts. About 132 participants will receive either the program plus usual care or usual care alone. Researcher…

This study looks at whether being awake between 2:00 and 4:00 AM makes negative mood, poor decision-making, and suicidal thoughts worse. Adults who have had suicidal thoughts in the past six months will be tested in a lab and at home under different sleep conditions. The goal is …

This study aims to create a treatment prognosis calculator for 1,200 active-duty military members with suicidal thoughts. The goal is to predict who will improve with standard care and who might benefit more from a specialized therapy called Brief Cognitive Behavioral Therapy (BC…

This study looks at how ketamine reduces suicidal thoughts in people with depression, bipolar disorder, or PTSD. Researchers want to see if blocking a specific brain receptor (AMPA) stops ketamine from working. 30 adults with current suicidal thoughts will receive ketamine with e…

This study tests a program called WeCare for Black youth ages 12-19 who visit emergency rooms and may be at risk for suicide. The program includes a quick screening, a brief safety planning session, and supportive text messages for six weeks. Researchers want to see if this appro…

This study looks at how to best help teenagers (ages 11-17) who have been hospitalized for suicidal thoughts or actions. Researchers will compare different support strategies to see which ones work best to prevent future suicide attempts and reduce suicidal thinking. The goal is …

This study tests a program called Project RISE that helps college students become more aware of their body's signals, like hunger and emotions. The goal is to see if this can reduce suicidal thoughts and eating disorder symptoms. About 200 students with past or current suicidal t…

This study is developing and testing a small-group program called THRiVE for veterans who left the military within the last year. The program is led by peers and focuses on improving mental health and reducing suicide risk. Up to 40 veterans will try the program and report on the…

This study aims to understand how cannabis use and withdrawal affect depression and suicide risk in teenagers aged 12-18 who use cannabis daily or near-daily. Researchers will use smartphone surveys multiple times a day to track mood, cannabis use, and suicidal thoughts in real t…

This study is testing a smartphone app designed to help young adults aged 16 to 30 who are having suicidal thoughts. The app lets users track their feelings and risk levels over two months. Researchers want to see if the app is easy to use and helpful for both patients and their …

This study tests a digital program called Flourish designed to help teens aged 12-17 who have been cyberbullied and are at risk for suicide. About 80 teens will either use Flourish plus answer questionnaires or just answer questionnaires alone. Researchers want to see if the prog…

This study looks at how a 9-week therapy called Engage & Connect changes brain activity related to social rewards in adults aged 50-80 who have depression and suicidal thoughts. Researchers will use brain scans to measure changes in areas linked to positive feelings. The goal is …

This study tests whether using a life history calendar—a simple grid that helps people recall important life events—can improve how accurately adults in Hong Kong remember and report past mental health problems. Researchers will compare the standard interview method with the cale…