New combo therapy aims to stop suicide in PTSD veterans
NCT ID NCT07238192
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding a brief crisis coping strategy (Crisis Response Planning) to a standard talk therapy (Cognitive Processing Therapy) can lower suicidal thoughts and behaviors in veterans with PTSD. About 190 active-duty service members and veterans with PTSD and recent suicidal thoughts will take part. The goal is to see if the combined approach is more effective than therapy alone.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 190 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2026
- Expected to finish
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Aug 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Active duty service member or veteran aged 18 or older eligible for military medical care. 2. Able to read, write, and speak English. 3. Meeting diagnostic criteria for PTSD or subthreshold PTSD (i.e., meeting diagnostic threshold for 3 of 4 symptom criteria within the past month) on the Clinician Administered PTSD Scale for DSM-5 (CAPS-5). 4. Active suicidal ideation within the past week as assessed by scoring ≥ 1 on Scale for Suicidal Ideation (SSI) item 4 (i.e., active suicidal ideation within the past month) or report an interrupted, aborted, or actual suicide attempt within the preceding month on the Self-Injurious Thoughts and Behaviors Interview-Revised (SITBI-R). 5. Regular use of an iPhone or Android smartphone. Exclusion Criteria: 1. Inability to comprehend and complete the consent and baseline screening questionnaires. 2. Current suicide or homicide risk meriting crisis intervention. 3. Serious mental health symptoms, such as mania, psychosis, alcohol or substance use disorders warranting immediate clinical attention based on interviewer assessment and clinical judgement. 4. Currently engaged in evidence-based psychotherapy for PTSD (e.g., Cognitive Processing Therapy, Prolonged Exposure Therapy, Written Exposure Therapy).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Carl R. Darnall Army Medical Center
RECRUITINGFort Hood, Texas, 76544-9800, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can group therapy help teens with suicidal thoughts?
- Can music soothe the inner pain of a suicidal crisis?
- Does the order of therapy skills change how well it prevents suicide attempts?
- Can a single shot of ketamine calm suicidal distress in the ER?
- Can a Psychedelic-Assisted therapy help veterans with PTSD?