SUICIDAL IDEATION
Clinical trials for SUICIDAL IDEATION explained in plain language.
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New therapy using sleep and daily routines shows promise in cutting suicide risk in young people
Disease control CompletedThis study tested a therapy called BE-SMART-DR in 65 teens and young adults with bipolar disorder or major depression who had suicidal thoughts or past attempts. The therapy teaches self-guided strategies to regularize sleep and daily rhythms to reduce short-term suicide risk. Pa…
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: Yale University • Aim: Disease control
Last updated May 26, 2026 07:33 UTC
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Online mentors shield trans teens from drugs, violence, and depression
Prevention CompletedThis study tested an online mentoring program for transgender and gender minority youth ages 14 to 18. The program paired each teen with an adult transgender mentor for seven group sessions focused on building social and emotional skills. The goal was to prevent problems like dru…
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: University of Michigan • Aim: Prevention
Last updated May 26, 2026 07:24 UTC
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Can mindfulness ease pain and save lives? VA study tests new approach
Symptom relief CompletedThis pilot study tested whether a mindfulness program is acceptable and helpful for veterans with chronic pain who are also at risk for suicide. 76 veterans took part. The goal was to see if the program could reduce pain-related disability and suicide risk. Results will show if t…
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: Canandaigua VA Medical Center • Aim: Symptom relief
Last updated May 26, 2026 07:41 UTC
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Nasal spray vs. brain stimulation: which stops suicidal thoughts faster?
Symptom relief CompletedThis study tested if a nasal spray (esketamine) works as well as electroconvulsive therapy (ECT) for quickly reducing suicidal thoughts in people with depression. 340 adults with mood disorders and active suicidal ideation took part. The goal was to see if esketamine could be a l…
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: Capital Medical University • Aim: Symptom relief
Last updated May 26, 2026 07:40 UTC
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New program aims to bridge depression treatment gap for black youth
Symptom relief CompletedThis study tested a short program called Making Connections Intervention (MCI) to help Black adolescents with depression and suicidal thoughts engage in school-based treatment. 29 Black students in grades 6-12 participated. The program included 1-2 sessions plus digital tools to …
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: New York University • Aim: Symptom relief
Last updated May 26, 2026 07:33 UTC
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Magic mushroom compound shows promise for suicidal depression
Symptom relief CompletedThis study tested a single 25mg dose of psilocybin (the active ingredient in magic mushrooms) in 20 adults with depression that didn't respond to standard treatments and who also had ongoing suicidal thoughts. The goal was to see if the drug is safe and tolerable when given in a …
Matched conditions: SUICIDAL IDEATION
Phase: PHASE2 • Sponsor: Sheppard Pratt Health System • Aim: Symptom relief
Last updated May 26, 2026 07:33 UTC
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At-Home brain zaps show promise in preventing suicidal thoughts
Symptom relief CompletedThis study tested whether a safe, non-invasive brain stimulation technique called tDCS could be used at home to help prevent suicidal thoughts in adults recently discharged from the hospital for mood disorders. Thirty-three participants were randomly assigned to receive either re…
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: University of Rochester • Aim: Symptom relief
Last updated May 26, 2026 07:25 UTC
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Therapy tames tantrums: new hope for angry kids
Symptom relief CompletedThis study tested if adding cognitive behavioral therapy (CBT) to usual care helps reduce irritability and suicidal thoughts in children aged 8 to 12 with anger and aggression problems. 46 children from a mental health clinic were assigned to either CBT plus usual care or usual c…
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: Geha Mental Health Center • Aim: Symptom relief
Last updated May 26, 2026 07:24 UTC
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Phone alerts may curb suicidal urges in real time
Symptom relief CompletedThis study tested whether learning three skills to manage negative emotions and getting smartphone reminders to practice them can reduce how often and how intensely people feel emotional distress and suicidal thoughts. 41 adults with recent suicidal thoughts or a suicide attempt …
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated May 26, 2026 07:24 UTC
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Virtual programs show promise in reducing suicide risk among alaska native youth
Symptom relief CompletedThis study compared two virtual, culturally-tailored programs designed to reduce suicide risk and alcohol use in Alaska Native youth aged 14-24 who had been hospitalized for suicidal thoughts, attempts, or alcohol-related injuries. The programs focused on building coping skills a…
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: RAND • Aim: Symptom relief
Last updated May 26, 2026 07:23 UTC
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Hope in a classroom: new class aims to cut suicide risk after an attempt
Symptom relief CompletedThis study tested a 12-week class called Living with Hope for people who had recently attempted suicide. The class taught coping skills based on cognitive behavioral therapy (CBT). Researchers measured changes in suicidal thoughts, hopelessness, and depression over time. The goal…
Matched conditions: SUICIDAL IDEATION
Sponsor: University of Manitoba • Aim: Symptom relief
Last updated May 22, 2026 14:03 UTC
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Nightmare therapy shows promise for Kids' mental health
Symptom relief CompletedThis study tested a brief therapy called CBT-NC in 57 children ages 6-17 who have chronic nightmares. The goal was to see if the therapy could reduce nightmare distress and frequency, and in turn improve mental health and lower suicidal thoughts. Children were randomly assigned t…
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: University of Oklahoma • Aim: Symptom relief
Last updated May 20, 2026 11:57 UTC
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New program aims to combat loneliness and suicide in hispanic community
Symptom relief CompletedThis study tested a program called SOCIAL-ENGAGE designed to help Spanish-speaking adults who feel isolated and have thoughts of suicide. The program aims to increase their connections to their culture and community. Researchers worked with 54 participants to see if the program c…
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: University of Rochester • Aim: Symptom relief
Last updated May 20, 2026 11:57 UTC
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Texts that heal: new study tests phone messages for young adults avoiding therapy
Symptom relief CompletedThis study tested an 8-week text messaging program for young adults aged 18-25 with depression or anxiety who were not interested in or couldn't access in-person therapy. Participants received personalized or standard text messages, or weekly links to mental health info. The goal…
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: Northwestern University • Aim: Symptom relief
Last updated May 18, 2026 12:11 UTC
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Can a smartphone app curb self-harm in young adults?
Symptom relief CompletedThis study tested a digital mental health app for young adults (ages 18-25) who self-injure and are not in therapy. 90 participants were split into three groups: a self-guided app, the app with coaching, or an active control with educational content. The goal was to see if the ap…
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: Northwestern University • Aim: Symptom relief
Last updated May 18, 2026 12:09 UTC
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Ketamine shows promise for rapid relief of suicidal ideation
Symptom relief CompletedThis study tested whether ketamine, given as two infusions, can quickly reduce suicidal thoughts in 156 patients hospitalized for suicide risk. The main goal was to see if suicidal ideas resolved within 24 hours after the second dose. The approach aims to provide fast, short-term…
Matched conditions: SUICIDAL IDEATION
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 18, 2026 12:08 UTC
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Teen suicide prevention app shows promise in small pilot
Symptom relief CompletedThis study tested a new app designed to help teenagers aged 12-17 who are having suicidal thoughts. The app, called BackUp, was adapted from an adult version and includes a safety plan to help users identify coping strategies and support. Researchers wanted to see if teens found …
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: University Ghent • Aim: Symptom relief
Last updated May 18, 2026 12:02 UTC
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New screening tool could help prevent suicide in youth with autism
Knowledge-focused CompletedThis study tested a set of questions to better identify suicide risk in young people aged 8–17 with autism or other neurodevelopmental disorders. Researchers asked 278 participants and their parents about thoughts of self-harm and understanding of death. The goal was to create a …
Matched conditions: SUICIDAL IDEATION
Sponsor: National Institute of Mental Health (NIMH) • Aim: Knowledge-focused
Last updated May 26, 2026 07:39 UTC
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Small study tests suicide prevention in Low-Resource areas
Knowledge-focused CompletedThis study tested whether a suicide prevention package could be added to an existing depression program in rural Pakistan. Researchers worked with 50 women who had young children or were pregnant. The goal was to see if the program was practical and well-received, not to prove it…
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: Yale University • Aim: Knowledge-focused
Last updated May 26, 2026 07:37 UTC
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Hormone swings linked to suicide risk in women
Knowledge-focused CompletedThis study looked at 124 women with recent suicidal thoughts to understand how natural hormone changes during the menstrual cycle might increase suicide risk. Researchers used a two-week hormone-stabilizing treatment to see if it could reduce suicidal thinking around the time of …
Matched conditions: SUICIDAL IDEATION
Phase: PHASE4 • Sponsor: University of Illinois at Chicago • Aim: Knowledge-focused
Last updated May 26, 2026 07:32 UTC
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Can a phone app stop suicide? new study says maybe.
Knowledge-focused CompletedThis study tested a smartphone app called MAPS designed to help people who have suicidal thoughts or behaviors. 31 adults who had recent suicidal thoughts used the app, and researchers checked if it was easy to use and if people liked it. The goal was to see if the app could be a…
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: Butler Hospital • Aim: Knowledge-focused
Last updated May 26, 2026 07:26 UTC
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Can a navigator guide black teens from ER to mental health care?
Knowledge-focused CompletedThis study tested a program to help Black youth (ages 6-18) who came to the emergency room with suicidal thoughts or self-harm. The program, called STAT-ED, was adapted for Black youth and their families. It used a patient navigator to help them start and keep up with mental heal…
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: Children's Hospital of Philadelphia • Aim: Knowledge-focused
Last updated May 26, 2026 07:26 UTC
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Can a smartphone app reduce suicide risk? new study tests WisePath
Knowledge-focused CompletedThis study tested a mobile app called WisePath designed to help adults struggling with suicidal thoughts and alcohol misuse. 127 participants used either WisePath or a control app for 12 weeks. Researchers measured changes in suicidal thoughts, coping skills, and alcohol use to s…
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: Evidence-Based Practice Institute, Seattle, WA • Aim: Knowledge-focused
Last updated May 26, 2026 07:25 UTC
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Men with suicidal thoughts help design life-saving tools
Knowledge-focused CompletedThis study brought together men who had experienced suicidal thoughts to help create tools for suicide prevention. In up to 10 meetings, 13 men shared their needs and feedback on drafts and prototypes. The goal was to make sure the final tools are practical and truly helpful for …
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: University Ghent • Aim: Knowledge-focused
Last updated May 26, 2026 07:25 UTC
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Emergency room suicide prevention plan put to the test
Knowledge-focused CompletedThis study looked at whether a safety-planning intervention, already shown to help U.S. veterans, can work in a busy emergency department for adults who have attempted suicide or have severe suicidal thoughts. Researchers measured how often the plan was used and how satisfied pat…
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: Instituto de Investigación Hospital Universitario La Paz • Aim: Knowledge-focused
Last updated May 22, 2026 14:01 UTC
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Brain scan hunt for suicide clues
Knowledge-focused CompletedThis study looked for biological signs (biomarkers) that could help predict suicide risk in people with major depression. Researchers used brain scans to measure how the brain processes pain, reward, and attention. 97 adults with depression took part, but no treatment was given. …
Matched conditions: SUICIDAL IDEATION
Sponsor: Unity Health Toronto • Aim: Knowledge-focused
Last updated May 20, 2026 11:57 UTC
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New e-learning boosts doctors' skills in helping men at risk of suicide
Knowledge-focused CompletedThis study looked at whether an online training course could help healthcare providers feel more confident and capable when supporting men who are having suicidal thoughts. 119 doctors, nurses, and therapists completed the e-learning and filled out surveys about their skills. The…
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: University Ghent • Aim: Knowledge-focused
Last updated May 20, 2026 11:57 UTC
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Can a phone app help stop suicide? small study says maybe.
Knowledge-focused CompletedThis study tested a new smartphone app called MAPS designed to help people who are having suicidal thoughts. Ten adults who had recent suicidal thoughts used the app, and researchers checked if it was easy to use and if people liked it. The goal was to see if the app is a good to…
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: Butler Hospital • Aim: Knowledge-focused
Last updated May 20, 2026 11:56 UTC
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Community health workers boost suicide care for latinx youth
Knowledge-focused CompletedThis study tested a program where trained community health workers helped primary care clinics better identify and support Latinx teenagers at risk for suicide. The program included safety planning, parent education, and care coordination over 6-8 phone sessions. Researchers meas…
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated May 18, 2026 12:10 UTC