SUICIDAL IDEATION
Clinical trials for SUICIDAL IDEATION explained in plain language.
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Magic mushroom compound tested as potential lifeline for deepest depression
Disease control CompletedThis study tested whether a single, supervised dose of psilocybin (the active compound in 'magic mushrooms') is safe and can help people with severe depression that hasn't responded to other treatments, and who also have ongoing suicidal thoughts. It involved 20 adults who had no…
Matched conditions: SUICIDAL IDEATION
Phase: PHASE2 • Sponsor: Sheppard Pratt Health System • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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New school program aims to bridge treatment gap for depressed black teens
Disease control CompletedThis study tested a short program called the Making Connections Intervention (MCI) designed to help Black teenagers with depression feel more comfortable starting and sticking with treatment. The program, delivered in schools, used digital tools and personal sessions to make ther…
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: New York University • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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ER safety plan tested to stop suicide repeats
Disease control CompletedThis study tested whether a 'Safety Plan' tool could be successfully used in a busy emergency department to help people at immediate risk of suicide. The plan helps patients identify warning signs, coping strategies, and people to contact during a crisis. Researchers wanted to se…
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: Instituto de Investigación Hospital Universitario La Paz • Aim: Disease control
Last updated Mar 12, 2026 13:52 UTC
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New hope for suicidal thoughts: nasal spray challenges shock therapy
Disease control CompletedThis study tested whether a nasal spray medication called esketamine works as well as electroconvulsive therapy (ECT) for reducing suicidal thoughts in people with depression. Researchers compared the two treatments in 340 adults over 12 weeks to see which was better at quickly e…
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: Capital Medical University • Aim: Disease control
Last updated Mar 09, 2026 14:23 UTC
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New tool aims to spot suicide risk in autistic youth
Diagnosis CompletedThis study aimed to test a short questionnaire designed to identify suicide risk in children and teenagers with autism or similar conditions. Researchers worked with 278 youth and their parents to see if the questions accurately detected thoughts of self-harm. The goal is to crea…
Matched conditions: SUICIDAL IDEATION
Sponsor: National Institute of Mental Health (NIMH) • Aim: Diagnosis
Last updated Mar 25, 2026 14:07 UTC
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Virtual mentors step in to shield trans youth from harm
Prevention CompletedThis study tested an online mentoring program designed to prevent serious problems like depression, anxiety, substance use, and violence among transgender and gender minority teens. The program connected 56 youth, aged 14 to 18, with adult mentors from similar backgrounds for sev…
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: University of Michigan • Aim: Prevention
Last updated Apr 03, 2026 21:25 UTC
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Community program aims to stop suicide in High-Risk mothers
Prevention CompletedThis study tested a suicide prevention program designed for mothers in rural Pakistan. Researchers wanted to see if this program could be successfully added to existing community mental health services. They worked with 50 women who were pregnant or had young children and were at…
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: Yale University • Aim: Prevention
Last updated Apr 01, 2026 14:43 UTC
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New therapy aims to save young lives by fixing sleep and brain patterns
Prevention CompletedThis Yale University study tested a new therapy designed to prevent suicide in adolescents and young adults with depression or bipolar disorder. The therapy teaches self-help strategies to create more regular daily routines, especially for sleep, with the goal of improving brain …
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: Yale University • Aim: Prevention
Last updated Mar 30, 2026 14:30 UTC
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At-Home brain zaps tested to stop suicidal thoughts
Prevention CompletedThis study tested whether a home-based brain stimulation treatment could help prevent suicidal thoughts in adults at high risk after leaving the hospital. Researchers enrolled 33 adults with mood disorders who had recently been hospitalized for suicidal thoughts but were not acti…
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: University of Rochester • Aim: Prevention
Last updated Mar 30, 2026 14:28 UTC
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New program aims to fight loneliness and suicide risk in hispanic community
Prevention CompletedThis study tested a program called SOCIAL-ENGAGE, designed to help Spanish-speaking Hispanic adults who feel isolated and are at risk for suicide. The program aimed to increase their participation in cultural and social activities to build a stronger sense of community and belong…
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: University of Rochester • Aim: Prevention
Last updated Mar 09, 2026 14:23 UTC
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Can a smartphone app help curb suicidal thoughts?
Symptom relief CompletedThis study tested a mobile app called WisePath, designed to help adults cope with suicidal thoughts and problematic alcohol use. 127 participants were randomly assigned to use either the WisePath app or a different set of wellness resources for 12 weeks. Researchers measured chan…
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: Evidence-Based Practice Institute, Seattle, WA • Aim: Symptom relief
Last updated Apr 03, 2026 21:26 UTC
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Can text messages ease anxiety and depression in young adults?
Symptom relief CompletedThis study tested an 8-week text messaging program designed to help young adults (ages 18-25) who experience depression and anxiety but are not interested in traditional therapy. Researchers compared a personalized text message system that adapted to each person's needs against a…
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: Northwestern University • Aim: Symptom relief
Last updated Apr 03, 2026 14:42 UTC
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Phone app aims to be a lifeline for those in crisis
Symptom relief CompletedThis study tested a new smartphone app called MAPS, designed to help people manage suicidal thoughts and prevent crises. Researchers worked with 31 adults who had recent suicidal thoughts to see if the app was easy to use, acceptable, and safe. The goal was to check if using the …
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: Butler Hospital • Aim: Symptom relief
Last updated Apr 03, 2026 14:41 UTC
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VA tests mindfulness to ease pain and curb suicide risk in veterans
Symptom relief CompletedThis study tested whether a mindfulness training program was a practical and acceptable way to help veterans. The goal was to reduce the impact of chronic pain and lower the risk of suicide. 76 veterans with both chronic pain and suicidal thoughts were randomly assigned to either…
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: Canandaigua VA Medical Center • Aim: Symptom relief
Last updated Apr 02, 2026 14:57 UTC
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Phone alerts fight suicidal urges
Symptom relief CompletedThis study tested whether a smartphone app that sends reminders to practice emotional coping skills could help reduce suicidal thoughts. It involved 41 adults who were recently hospitalized for suicidal thoughts or attempts. Half received the app with daily prompts to practice sk…
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Apr 02, 2026 14:56 UTC
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Ketamine tested as Fast-Acting treatment for suicidal crisis
Symptom relief CompletedThis study tested whether ketamine, given as an infusion, could provide rapid relief from suicidal thoughts in people hospitalized for suicide risk. In this Phase 3 trial, 156 participants were randomly assigned to receive either ketamine or a placebo to see which was more effect…
Matched conditions: SUICIDAL IDEATION
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Apr 01, 2026 14:43 UTC
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Can your phone help save a life? app tested for suicide prevention
Symptom relief CompletedThis study tested a new smartphone app designed to help people experiencing suicidal thoughts. Researchers wanted to see if the app was practical, safe, and acceptable to use. They enrolled 10 adults who had recent suicidal thoughts to try the app and provide feedback.
Matched conditions: SUICIDAL IDEATION
Phase: NA • Sponsor: Butler Hospital • Aim: Symptom relief
Last updated Mar 30, 2026 14:28 UTC
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Virtual 'Living with Hope' class aims to curb suicidal thoughts
Symptom relief CompletedThis study tested a 12-week online class called 'Living with Hope' for adults who had recently attempted suicide. The class taught coping skills based on cognitive behavioral therapy. Researchers wanted to see if the class safely reduced suicidal thoughts and behaviors, and if im…
Matched conditions: SUICIDAL IDEATION
Sponsor: University of Manitoba • Aim: Symptom relief
Last updated Mar 17, 2026 12:55 UTC
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Scientists search for Brain's suicide warning signs
Knowledge-focused CompletedThis study aimed to find biological markers, or signs, that could help predict suicide risk in people with major depression. Researchers used brain scans, thinking tests, and behavioral tasks to measure how people process pain, reward, and attention. They followed 97 adults with …
Matched conditions: SUICIDAL IDEATION
Sponsor: Unity Health Toronto • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC
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Scientists test if hormone pills can curb monthly suicide risk spike
Knowledge-focused CompletedThis study investigated why suicidal thoughts often worsen around a woman's period. Researchers gave 124 women with recent suicidal thoughts either a hormone-stabilizing treatment or a placebo for two weeks around their menstrual cycle. The goal was to see if preventing the natur…
Matched conditions: SUICIDAL IDEATION
Phase: PHASE4 • Sponsor: University of Illinois at Chicago • Aim: Knowledge-focused
Last updated Mar 19, 2026 14:56 UTC