PREECLAMPSIA

This early-stage trial tested the safety and tolerability of telpegfilgrastim injections in 18 non-pregnant women, including some with a history of preeclampsia. Researchers monitored side effects, drug levels in the blood, and immune markers. The goal is to see if the drug is sa…

This study looked at 60 women with preeclampsia having a C-section to find the best doses of two drugs (phenylephrine and norepinephrine) to prevent dangerously low blood pressure after spinal anesthesia. The goal was to identify doses that work in 90% of patients. The findings c…

This completed study compared two intravenous blood pressure medications, labetalol and hydralazine, in 132 pregnant women with severe preeclampsia. The goal was to see which drug more effectively lowered blood pressure to safe levels. Results could help doctors in the local sett…

This study tested a medical device that filters a harmful protein called sFlt-1 from the blood of pregnant women with preeclampsia, a serious condition causing high blood pressure. The goal was to see if the treatment is safe and can help control the disease. The trial involved 2…

This study looked at whether giving magnesium sulfate for 12 hours after childbirth is as effective as the usual 24 hours for preventing seizures in women with mild preeclampsia. Researchers enrolled 200 women and measured blood pressure, symptoms, and treatment duration. The goa…

This study looked at 390 women with preeclampsia having a C-section under spinal anesthesia. Researchers compared two different blood pressure targets to see which one led to better outcomes for the baby. The goal was to find the safest way to manage blood pressure drops during t…

This study looked at whether a special ultrasound score (called VEXUS) can predict acute kidney injury in pregnant women with severe preeclampsia. Researchers enrolled 70 women and checked the accuracy of the score at hospital admission. The goal is to identify those at risk earl…

This study looked at whether a protein called Cadherin-6 in the blood of pregnant women could help predict preeclampsia, a dangerous condition involving high blood pressure. Researchers measured Cadherin-6 levels in 150 women between 15 and 20 weeks of pregnancy and tracked who l…

This study looked at whether a blood test called the sFlt-1/PlGF ratio can help doctors make better decisions for pregnant women with suspected preeclampsia before 35 weeks. The goal was to see if using the test improves care for both mother and baby and lowers hospital costs. 84…

This study looked at how aspirin works in pregnant women at high risk for preeclampsia, a serious blood pressure disorder. Researchers measured platelet function and genetic factors in 130 women to understand why some still develop the condition. The goal is to personalize aspiri…

This study collected blood samples from 236 pregnant women with and without preeclampsia. The goal was to test a new approach that filters out a protein called sFlt-1 from the blood, which may help restore normal blood vessel function. The research is a first step toward a possib…

This study tested whether a pop-up alert in electronic health records could increase doctors' recommendations for low-dose aspirin in pregnant women at high risk for preeclampsia. Over 800 women were included, and the alert was shown during prenatal visits. The goal was to see if…

This study looked at whether a 4-week resistance training program is doable for women who had pregnancy complications like preeclampsia or preterm birth. Seven new moms participated, and researchers measured how well they stuck with the exercises and how they felt about them. The…

This study examined heart function in 80 pregnant women—40 with preeclampsia and 40 healthy—to see how preeclampsia affects the heart's ability to relax. Researchers used ultrasound to measure diastolic function. The goal was to better understand heart risks in preeclampsia, not …

This study looked at whether low vitamin D levels in the first trimester of pregnancy are linked to developing preeclampsia later on. Researchers measured vitamin D in over 3,000 pregnant women in France. The goal was to understand how common vitamin D deficiency is and if it rel…

This study looked at how giving IV fluids during a C-section affects heart function in women with preeclampsia. Researchers used ultrasound to measure heart output in 34 women. The goal was to better understand how to manage fluids safely in these patients.

This study looked at whether special ultrasound measurements of the baby's kidney and placenta can help predict health problems in newborns. Researchers compared 114 pregnant women with and without preeclampsia. The goal was to see if these scans could warn doctors about complica…

This study tested a special nursing program that teaches pregnant women with preeclampsia about climate-related health risks, like heat and pollution. 104 women took part, with half receiving the program plus usual care and half receiving usual care alone. The goal was to see if …

This study measured levels of a protein called CD71 in placentas from 39 women with preeclampsia and 39 with normal blood pressure during pregnancy. Researchers wanted to see if CD71 is linked to placental problems and how it relates to newborn health. The goal is to better under…

This study looked at how aspirin affects immune cells (neutrophils) in pregnant women at high risk of preeclampsia. Researchers took blood samples from 35 women at different times during pregnancy to see why some women still develop preeclampsia despite taking aspirin. The goal w…

This study followed 72 pregnant women with HELLP syndrome, a serious complication of preeclampsia, to see how their blood markers changed daily before and after delivery. Researchers measured platelets, liver enzymes, and lactate dehydrogenase levels. The goal was to better under…