PERIODONTAL DISEASE
Clinical trials for PERIODONTAL DISEASE explained in plain language.
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Scientists test two gels to rebuild lost jawbone from gum disease
Disease control CompletedThis study compared two treatments for rebuilding bone lost to severe gum disease. 26 patients with one deep bone defect had surgery and received either a platelet-rich fibrin (PRF) gel or an enamel-derived protein gel (EMD). Researchers measured gum pocket depth and bone attachm…
Matched conditions: PERIODONTAL DISEASE
Phase: PHASE4 • Sponsor: Semmelweis University • Aim: Disease control
Last updated Apr 04, 2026 05:19 UTC
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Phone app aims to boost nutrition and fight gum disease for expectant moms
Disease control CompletedThis study tested whether a special mobile app called NutriDent4Mom could help pregnant women improve their diet and gum health. Researchers compared the app to standard pregnancy health programs. The goal was to see if using the app led to better nutrient intake, healthier eatin…
Matched conditions: PERIODONTAL DISEASE
Phase: NA • Sponsor: NORKHAFIZAH SADDKI • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Laser light boosts gum healing in smokers, study finds
Disease control CompletedThis study tested whether adding a special laser treatment to standard deep cleaning improves gum health for smokers with severe gum disease. Thirty-three smokers received either the standard cleaning alone or the cleaning plus laser therapy. After three months, the group that re…
Matched conditions: PERIODONTAL DISEASE
Phase: NA • Sponsor: Selcuk University • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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Scientists search for missing link between diabetes and gum health
Knowledge-focused CompletedThis study aimed to understand the connection between type 2 diabetes and gum disease by measuring levels of three minerals—chromium, magnesium, and nickel—in the blood. Researchers compared 74 adults with different health statuses: healthy individuals, those with gum disease onl…
Matched conditions: PERIODONTAL DISEASE
Sponsor: Kahramanmaras Sutcu Imam University • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:41 UTC
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Scientists probe viral link to Radiation-Induced dental damage
Knowledge-focused CompletedThis study aimed to understand why severe gum disease is so common after radiation treatment for head and neck cancers. Researchers followed 25 patients to see if radiation changes the levels of a common virus (Epstein-Barr virus) in the gums. The goal was to gather knowledge to …
Matched conditions: PERIODONTAL DISEASE
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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Could your gum health be tied to Alzheimer's? new study investigates blood clues
Knowledge-focused CompletedThis study aimed to investigate a possible link between gum disease (periodontitis) and Alzheimer's disease by analyzing blood test results. Researchers compared 100 people who had both conditions to people who had gum disease alone. They looked for patterns in standard blood cel…
Matched conditions: PERIODONTAL DISEASE
Sponsor: Uskudar University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:33 UTC
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Smokers' addiction may blind them to gum disease warning signs
Knowledge-focused CompletedThis study looked at whether a person's level of nicotine addiction affects how aware they are of their gum disease. Researchers surveyed and examined 350 adult smokers who had gingivitis or periodontitis. The goal was to understand if stronger addiction makes people less likely …
Matched conditions: PERIODONTAL DISEASE
Sponsor: Erzincan University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:32 UTC
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Scientists search for hidden gum disease in bridge patients
Knowledge-focused CompletedThis study aimed to better understand gum health in people who need fixed dental bridges. Researchers measured specific inflammation markers in the gum fluid of 90 patients to detect early signs of gum disease that might not be visible during a regular dental check-up. The goal w…
Matched conditions: PERIODONTAL DISEASE
Sponsor: Jagiellonian University • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:40 UTC
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Could your gum health affect your eyes? scientists investigate
Knowledge-focused CompletedThis study aimed to understand if there is a link between gum disease (periodontitis) and a serious inflammatory eye disease called non-infectious uveitis. Researchers compared 25 patients with the eye condition to 27 healthy people, checking their gum health and measuring levels…
Matched conditions: PERIODONTAL DISEASE
Sponsor: Selcuk University • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
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Scientists search for gum disease clues in spit
Knowledge-focused CompletedThis study aimed to understand gum disease better by comparing levels of specific proteins in saliva and gum fluid between people with periodontitis and healthy individuals. Researchers enrolled 44 participants—half with gum disease and half without—and measured these protein lev…
Matched conditions: PERIODONTAL DISEASE
Sponsor: Melis Yilmaz • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:19 UTC
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Scientists search for hidden link between weak bones and bad gums
Knowledge-focused CompletedThis study aimed to understand the biological connection between osteoporosis (bone loss) and periodontal disease (gum disease) in women after menopause. Researchers measured specific proteins related to inflammation and bone breakdown in the blood and gum fluid of 80 participant…
Matched conditions: PERIODONTAL DISEASE
Sponsor: Recep Tayyip Erdogan University • Aim: Knowledge-focused
Last updated Mar 09, 2026 14:25 UTC
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Scientists search for hidden links between diabetes and gum health
Knowledge-focused CompletedThis study aimed to better understand the biological connections between type 2 diabetes and gum disease (periodontitis). Researchers enrolled 226 adults, with and without these conditions, to collect blood and saliva samples. The goal was to measure immune system signals and bac…
Matched conditions: PERIODONTAL DISEASE
Phase: NA • Sponsor: Sanofi Pasteur, a Sanofi Company • Aim: Knowledge-focused
Last updated Mar 03, 2026 14:07 UTC