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Gum bone repair: PRF gel vs. enamel matrix in head-to-head trial

NCT ID NCT07183631

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 28 times

Summary

This study tested two treatments for deep bone defects caused by gum disease: platelet-rich fibrin (PRF) gel and enamel matrix derivative (EMD). Twenty-six adults with advanced chronic periodontitis received one of the two treatments during surgery. Researchers measured gum attachment levels and pocket depths at 6 months and 3 years to see which worked better long-term.

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Contacts and locations

Locations

  • Semmelweis University

    Budapest, 1088, Hungary

Conditions

Explore the condition pages connected to this study.