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Tiny metals in blood may link diabetes and gum troubles

NCT ID NCT07327086

Knowledge-focused Sponsor: Kahramanmaras Sutcu Imam University Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study measured levels of three metals—chromium, nickel, and magnesium—in the blood of 74 adults. Some had type 2 diabetes and gum disease, some had only one condition, and some were healthy. The goal was to see if these metals are connected to gum health in people with diabetes. No treatment was given; it was purely an observational study.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

74 people

The number who actually took part.

Started

Jul 2025

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consists of adult individuals aged 18 years and older who were systemically evaluated at the Department of Endocrinology and Metabolism and subsequently referred for periodontal examination. Participants include systemically and periodontally healthy individuals as well as patients diagnosed with chronic periodontitis, with or without type 2 diabetes mellitus. Eligible participants were allocated into study groups based on periodontal status and glycemic control.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged ≥18 years * Having at least 20 natural teeth, excluding third molars * Diagnosed with type 2 diabetes mellitus or systemically healthy, according to group allocation * Willingness to participate in the study and provision of written informed consent Exclusion Criteria: * Presence of systemic diseases other than type 2 diabetes mellitus (e.g., renal or hepatic failure, cardiovascular disease, organ transplantation, or current or previous cancer treatment) * Use of antibiotics, non-steroidal anti-inflammatory drugs, corticosteroids, immunosuppressive drugs, calcium channel blockers, beta blockers, oral contraceptives, or anticoagulants within the last 3 months * History of non-surgical periodontal treatment within the last 6 months or periodontal surgery within the last 12 months * Pregnancy or lactation * Body mass index (BMI) ≥ 30 kg/m² * Current smoking or alcohol consumption * Use of vitamin, mineral, or antioxidant supplements within the last 3 months

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Conditions

The condition(s) this trial relates to.

chronic periodontitis periodontal disorder type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Periodontal disease Type 2 diabetes mellitus (T2DM)

Contacts and locations

Locations

  • Kahramanmaraş Sütçü İmam University

    Kahramanmaraş, Turkey (Türkiye)

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