PAIN, ACUTE

This study tested a 6-week nurse-led program to help breastfeeding women manage breast and nipple pain. About 250 new mothers who planned to breastfeed took part. The program used a smartphone app to teach pain management skills and offered support through text messaging. Results…

This study tested two methods of pain control after hip replacement surgery in 60 adults. One group received a continuous nerve block near the spine (erector spinae plane block), while the other received standard epidural pain relief. Researchers measured pain levels, opioid use,…

This study tested whether breathing hydrogen gas before and after surgery could reduce pain and inflammation in 37 people having back surgery for a herniated disc. Researchers measured pain levels and blood markers of inflammation. The goal was to see if hydrogen inhalation is a …

This study compared two types of nerve blocks (ESP and QL block) to see which one better controls pain after abdominal surgery. 100 adults having surgery for cancers or gallbladder issues received one of the blocks before their operation. Researchers measured how much strong pain…

This study tested whether using virtual reality (VR) can lower the pain people feel from brief, hot sensations. Twenty-four healthy adults received short, painful-but-tolerable heat pulses on their skin, sometimes while wearing a VR headset and sometimes without. They rated their…

This study tested whether a virtual reality program that uses biofeedback (like heart rate monitoring) could help children and teenagers aged 12-18 manage pain after surgery. 93 participants used the program before and after their operation. The goal was to see if the approach wa…

This study tested two methods to control pain after gallbladder removal: a nerve block (external oblique intercostal block) versus injecting pain medicine into the surgical cuts (port-site infiltration). Sixty adults took part to see which approach lowered pain and the need for s…

This study looked at 46 adults having spinal surgery to see if giving a nerve block (ESP block) before or after surgery makes a difference in pain and recovery. The goal was to find out which timing reduces the need for strong painkillers and helps patients feel better sooner. Re…

This study tested a new online program that teaches mindfulness and coping skills to people recovering from surgery. The program is completely self-guided, meaning no therapist is needed. Researchers wanted to see if people would find it useful and easy to use compared to a works…

This study tested whether stimulating the palmar grasp reflex (the natural reflex to grip a finger) can reduce pain and improve comfort in preterm babies during routine PICC line care. 32 preterm infants with a PICC line were included. Researchers measured pain levels and comfort…

This study tested whether breathing in morphine through a mask works as well as getting it through an IV for severe pain in the emergency room. 226 adults with intense pain were randomly assigned to receive either inhaled morphine plus a fake IV, or IV morphine plus a fake inhale…

This study looked at whether vitamin C can reduce pain sensitivity in healthy adults. 38 volunteers took either vitamin C or a placebo, and researchers measured how much pressure they could tolerate before feeling pain. The goal was to see if vitamin C could be a safe, non-drug o…

This study tested whether a numbing injection near the chest wall (serratus anterior plane block) can improve pain, breathing, and coughing in emergency room patients with broken ribs. Forty adults with rib fractures received either the injection or standard care. Researchers mea…

This study tested whether a medicine called dexmedetomidine (Precedex) can help control pain in adults with three or more broken ribs. The goal was to lower pain scores and reduce the need for strong opioid painkillers. 41 ICU patients took part, and researchers tracked their pai…

This study looked at whether taking ibuprofen for eight days after hip or knee replacement is safe. About 2904 adults took part. Researchers tracked serious problems like heart attack, stroke, bleeding, or kidney failure for 90 days after surgery.

This study looked at whether cognitive behavioral therapy (CBT) can help people who had surgery for a broken bone feel less pain over the next year. Over 1,000 adults took part, some getting CBT and others usual care. The goal was to see if CBT lowers the chance of developing lon…

This study looked at whether giving patients an open-label placebo (a pill they know has no active drug) can help manage sudden, non-specific pain in the emergency department. 57 adults with acute pain took part. The main goal was to see if this approach is practical and acceptab…

This study tested whether hand reflexology or a simple hand massage could help reduce pain, anxiety, and improve vital signs in 70 adults who had a coronary angiography (a heart procedure). Participants received one of the two massage techniques, and their pain and anxiety levels…

This study tested whether giving a low dose of ketamine over 30 minutes instead of 15 minutes reduces side effects like dizziness and confusion while still controlling severe pain. 55 adults with acute pain in the emergency department took part. The goal was to find a way to keep…

This study tested whether a mild electrical stimulation on the ear (transauricular vagal nerve stimulation) can change how healthy people sense internal body signals like pain, heartbeat, and temperature. Fifty healthy adults aged 18-60 took part. The goal was to understand the e…

This study looked at why some people feel a sharp increase in pain when a numbing injection (nerve block) wears off after surgery. Researchers gave 40 healthy adults a nerve block in one arm and measured their pain sensitivity as the numbness faded. The goal was to see if the ner…

This study measured how often hospitalized patients with cirrhosis experience pain. Researchers surveyed 30 adults at one French hospital, asking about pain presence, location, and intensity. The goal was to fill a gap in knowledge, since no French studies had looked at this befo…

This study looked at how short-term pain affects the ability to learn and remember new movement patterns in 61 healthy young and older adults. Researchers tested walking patterns and memory tasks to see if pain impairs learning and if older adults are more affected. The goal is t…

This study examined whether a person's body mass index (BMI) influences how well a nerve block controls pain after surgery for a slipped disc in the lower back. Researchers measured pain levels in 75 adults at different times after surgery. The goal was to see if higher BMI leads…