Which pain block works best after belly surgery?
NCT ID NCT05446727
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested two types of nerve blocks—Quadratus Lumborum (QL) and Erector Spinae (ESP)—to see which provides better pain relief after abdominal surgery. 100 adults having surgery for colorectal, prostate, or kidney cancer, or gallbladder removal, received one of the blocks before surgery. Researchers measured how much extra pain medicine they needed and their pain scores afterward.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- ropivacaine injection
- What this could lead to
- If one block works better, it could lead to better pain control and less opioid use after abdominal surgery.
- What could go wrong
- This is a small, completed study comparing two techniques. Results may not apply to all surgeries or patients. Both blocks have risks like infection or allergic reaction.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
100 people
The number who actually took part.
- Started
-
May 2022
- Finished
-
Dec 2023
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 90 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients requiring abdomen surgery * Patients of age 18 and over * BMI \< 40 * Patients who are expected to stay in-hospital overnight after surgery Exclusion Criteria: * Patient refusal * Contraindications to paravertebral blocks: Infection at the site of needle insertion, empyema, allergy to local anesthetic drugs, and tumor occupying the thoracic paravertebral space, coagulopathy, bleeding disorder or therapeutic anticoagulation * Known allergy to local anesthetics * Inability to provide informed consent * Inability to use a PCA due to languate or comprehension barriers * BMI \>= 40 * Any patient on opioids for greater than or equal to 3 months duration prior to surgery * Patients with chronic pain syndromes
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Jagiellonian University
Krakow, Maloposkie, 31-501, Poland
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