OSTEOARTHRITIS

This study is tracking how well Persona knee replacement implants perform over time in people with severe knee arthritis. Researchers are following 737 patients for up to 10 years after surgery to see how long the implants last and how much pain relief and improved function they …

This study aims to see if a newer, all-plastic knee implant part stays in place as well as a traditional metal-backed part over two years. It involves 60 people with severe knee osteoarthritis who are getting a total knee replacement. Researchers will use special X-ray scans to m…

This study is tracking a specific knee replacement implant over 10 years to see how well it reduces pain, improves mobility, and lasts inside the body. It involves about 300 adults with severe knee arthritis who receive the implant. Researchers will check in regularly using X-ray…

This study is following 240 people for 10 years after they receive a specific brand of personalized knee replacement. Researchers want to see how safe the implant is and how well it relieves pain and improves movement for people with severe knee arthritis. The study tracks patien…

This study is testing whether giving a single high dose of vitamin D before hip or knee replacement surgery to patients with low levels can help reduce complications like infections. It involves 200 adults with osteoarthritis and low vitamin D. Researchers want to see if this sim…

This study is tracking how well a new type of shoulder replacement implant works over time. It follows 152 patients with severe shoulder arthritis who received the implant, checking their pain, movement, and quality of life for up to 10 years after surgery. The main goal is to co…

This study is testing the safety and performance of a new hip replacement system called CATALYSTEM. It involves 119 adults with severe hip damage from conditions like arthritis. Researchers will follow patients for 10 years to see how well the implant holds up and improves their …

This study is tracking the safety and performance of a specialized metal plate used to fix broken shoulders. It will follow 135 adults who get this plate after a shoulder fracture to see how well they heal, how much their shoulder moves, and if they need another surgery. The main…

This study is testing how well a new knee replacement system works for patients who need a second or revision surgery. It's for people whose first knee replacement failed or who have severe arthritis, deformity, or pain. Researchers will track how well the new implant improves pa…

This study is observing how well a new hip replacement system works and how safe it is for patients with severe hip arthritis or similar conditions. It will follow 230 patients who receive the implant to see how long it lasts and how much it improves their pain and mobility. The …

This study is comparing two ways to perform total shoulder replacement surgery for people with severe arthritis. About 120 patients will be randomly assigned to get either the traditional surgery or a newer 'rotator cuff sparing' technique that avoids cutting a major shoulder ten…

This study compares two common treatments for people with knee arthritis and a torn meniscus (a piece of cartilage in the knee). Researchers want to know if surgery or a structured physical therapy program works better to improve knee function and reduce pain. About 350 adults wi…

This study is tracking how well a specific type of shoulder replacement implant works over time. It involves 200 adults with severe shoulder problems like arthritis or complex fractures who need a 'reverse' shoulder replacement. Researchers will follow patients to see how long th…

This study compares two types of knee replacement implants—one that uses bone cement and one that doesn't—to see which provides better long-term results. Researchers will follow 300 patients with severe knee arthritis for up to 5 years after surgery, measuring pain levels, knee f…

This early-stage study aimed to test the safety and feasibility of a single injection of a patient's own processed fat tissue into the knee to treat arthritis that developed after a significant injury. The goal was to see if this approach could help younger, active adults with pe…

This study is evaluating a new type of cementless knee replacement implant for people with severe osteoarthritis. It aims to see how well the implant improves daily activities, reduces pain, and holds up over time. Researchers will follow 540 patients for up to five years after s…

This study is collecting information on how well low-dose radiation therapy helps with pain and improves daily function for people with osteoarthritis. It will follow 40 patients who are already receiving this standard treatment, tracking their pain levels, medication use, and qu…

This study is testing whether two types of non-invasive brain stimulation can reduce pain and improve movement in people with chronic knee osteoarthritis. Researchers are comparing real stimulation to fake (sham) stimulation in 64 participants to see if it helps. The main goal is…

This study follows 777 adults who received Persona brand knee replacements for severe arthritis pain. Researchers will track how well the implants work and how long they last over 5-10 years. The goal is to collect real-world data on pain relief, joint function, and quality of li…

This study aimed to test a new, non-surgical procedure for people with chronic knee pain from arthritis who are not candidates for surgery. Doctors planned to inject a medication called doxycycline into tiny blood vessels around the knee to try to reduce pain. The goal was to see…

This study is testing whether a deep-heat therapy called short wave diathermy can help people with hand osteoarthritis. It will compare the therapy plus hand exercises against sham (fake) therapy plus exercises in 36 participants. The main goal is to see if the treatment reduces …

This study is testing whether special gloves can help reduce pain and improve hand function for people with hand osteoarthritis. The gloves are embedded with a material that emits gentle energy and negative ions, which researchers believe may increase blood flow and reduce inflam…

This study is testing whether capsules containing a concentrated turmeric extract can reduce pain and inflammation in adults with knee osteoarthritis. Researchers will compare the turmeric capsules to a placebo (a dummy pill with no active ingredient) over three weeks. The main g…

This study is creating a large national registry to track the experiences of 30,000 people who have hip or knee replacement surgery. By collecting detailed information before and after surgery, researchers aim to identify what leads to the best results and fewest complications. T…

This study aims to collect and analyze fluid from shoulder, hip, and knee joints to find biological markers that signal the earliest stages of osteoarthritis. Researchers hope these markers will help identify people at risk before symptoms appear, allowing for earlier interventio…

This study aims to understand how best to measure pain and physical function in people with knee osteoarthritis. Researchers will enroll 100 participants with moderate knee arthritis to compare different questionnaires and physical tests. The goal is to gather information that co…

This study looks at whether a new payment system called 'bundled payments' improves the quality of care while reducing costs. Researchers are analyzing Medicare data from 440 healthcare providers treating conditions like joint replacements, pneumonia, and COPD. The goal is to see…