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New knee implant tested for better mobility and pain relief

NCT ID NCT04817969

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 25 times

Summary

This study looks at how well a new knee implant (Persona Ti-Nidium) works for people with severe knee problems like arthritis or deformity. About 240 people who need a total knee replacement will get the implant and be followed for safety and function. The main goal is to see if patients report better knee function and less pain after surgery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Denver Hip & Knee, Inc.

    Parker, Colorado, 80134, United States

  • Duke University

    Durham, North Carolina, 27708, United States

  • MedStar Health Research Institute

    Hyattsville, Maryland, 20782, United States

  • Mississippi Sports Medicine and Orthopaedic Center

    Jackson, Mississippi, 39202, United States

  • Monument Health Rapid City Hospital, Inc.

    Rapid City, South Dakota, 57701, United States

  • New Mexico Orthopaedic Associates

    Albuquerque, New Mexico, 87110, United States

  • Rothman Orthopaedic Institute

    Philadelphia, Pennsylvania, 19107, United States

Conditions

Explore the condition pages connected to this study.