OSTEOARTHRITIS

This study tests a stem cell product called XytriX, made from umbilical cord cells, for treating knee osteoarthritis. About 75 adults with mild to severe knee arthritis will receive an injection into the knee joint. The goal is to see if it safely reduces pain and improves knee f…

This study looks at whether two common diabetes drugs—GLP1 and SGLT2—can reduce joint pain and stiffness in people with type 2 diabetes and osteoarthritis. About 390 adults over 50 who have taken one of these drugs for at least a year will report their pain and physical function.…

This study looks at whether a carefully planned ketogenic diet can help people who have both osteoarthritis (joint pain) and mild cognitive impairment (memory issues). Ten adults will follow the diet under supervision for a period, and researchers will measure changes in pain, ph…

This study will compare two types of total knee replacement surgery for people with knee osteoarthritis: one using a robotic device (VELYS) and the other done by hand. About 346 participants will be randomly assigned to one of the two methods. The goal is to see if the robotic ap…

This study tests whether applying bee venom gel to the skin with ultrasound (phonophoresis) can reduce pain and improve movement in people with knee osteoarthritis. Thirty adults aged 40 to 75 with moderate to severe knee pain will receive either the bee venom treatment or a plac…

This study tests whether a virtual, team-based lifestyle program works as well as in-person physiotherapy for people with chronic muscle or joint pain living in rural areas. About 354 adults with conditions like back pain or osteoarthritis will receive up to 10 sessions over six …

This study looks at whether taking a powder made from Rosa roxburghii (a type of rose fruit) can help people recover after total knee replacement surgery for osteoarthritis. About 184 adults will take either the fruit powder or a placebo daily for 30 days after surgery. Researche…

This study tests a new tablet called Laybon Tab. to see if it works as well as an existing drug for knee osteoarthritis pain. About 172 adults aged 40 to 80 with knee pain for at least 3 months will take the medicine for 8 weeks. The main goal is to measure changes in knee pain d…

This study tests a gel called Sensovisc that is injected into the hip joint to reduce pain and improve movement in people with hip osteoarthritis. The gel works by helping the joint's natural fluid work better. Researchers will measure pain and function in 25 adults over 6 months…

This study looks at joint tissue from 30 people with early knee osteoarthritis to identify different types of inflammation. Researchers will take small tissue samples using a needle guided by ultrasound, along with blood tests. The goal is to better understand how the disease sta…

This study looks at how many people with knee osteoarthritis also have sarcopenia, a condition where muscles become weak and shrink. Researchers will check muscle mass, strength, and physical performance in 224 adults aged 40 and older in Upper Egypt. The goal is to better unders…

This study looks at how people make decisions about imaging tests like X-rays or MRIs for common muscle and joint issues. About 220 adults with conditions like arthritis or carpal tunnel syndrome will either have a short conversation about the test's pros and cons or read brief i…

This study will use a high-tech blood test (mass spectrometry) to look at different immune cells in 500 people with various autoimmune diseases and healthy volunteers. The goal is to find patterns that could help doctors screen for and diagnose these conditions earlier. No new tr…

This study looks at 20 people with severe temporomandibular joint (TMJ) disorders who need surgery. Researchers will examine removed tissue for signs of bacteria and other clues to understand what causes these painful jaw conditions. The goal is to learn more about the disease, n…