AI takes on arthritis: could computers Out-Diagnose doctors?
NCT ID NCT07153315
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study will test whether artificial intelligence can accurately tell the difference between inflammatory arthritis (like rheumatoid arthritis) and degenerative arthritis (like osteoarthritis) in people aged 60 and older. Researchers will compare the AI's analysis of X-rays, MRIs, or ultrasounds against expert rheumatologists' diagnoses. If the AI proves reliable, it could become a tool to help doctors diagnose joint diseases more quickly and accurately.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- AI-assisted imaging analysis
- What this could lead to
- If successful, this could provide a faster, more reliable way to diagnose arthritis types in older adults, improving treatment decisions.
- What could go wrong
- This is an early-stage study with only 140 participants. The AI may not perform as well in real-world settings or with different imaging equipment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 140 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2025
An estimate. Start dates often move.
- Expected to finish
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Oct 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Elderly patients (≥60 years) presenting to Assiut University Hospitals with clinical suspicion or diagnosis of musculoskeletal disorders, specifically inflammatory joint diseases (such as rheumatoid arthritis) or degenerative joint diseases (such as osteoarthritis), and who have relevant imaging studies (X-ray, MRI, or ultrasound) available for analysis.
- Ages
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60 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria : 1. Age ≥ 60 years 2. Clinical suspicion or confirmed diagnosis of inflammatory joint disease (e.g., rheumatoid arthritis, psoriatic arthritis) or degenerative joint disease (e.g., osteoarthritis) 3. Availability of relevant musculoskeletal imaging (X-rays, MRI, or ultrasound) suitable for AI-based analysis 4. Ability to provide informed consent or have a legal representative consent on behalf of the Exclusion criteria: 1. History of recent joint trauma (within the last 6 months) or previous joint surgery affecting the studied sites 2. Presence of bone or joint malignancy (primary or metastatic) 3. Diagnosis of overlapping rheumatologic syndromes or mixed pathology (e.g., RA with concurrent gout, or OA with inflammatory overlap) 4. Inadequate imaging quality or absence of required imaging modalities 5. Inability or unwillingness to provide informedconsent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Assiut University Hospital
Asyut, 71515, Egypt
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