OSTEOARTHRITIS
Clinical trials for OSTEOARTHRITIS explained in plain language.
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Knee osteoarthritis drug trial halted midway
Disease control TerminatedThis study tested an experimental drug called LNA043, given as a shot into the knee, to see if it could slow down cartilage loss and reduce pain in people with knee osteoarthritis. The trial planned to follow 576 adults aged 40 to 75 for up to 5 years, but it was stopped early. T…
Matched conditions: OSTEOARTHRITIS
Phase: PHASE2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated May 26, 2026 07:58 UTC
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Knee surgery pain study: does an extra block help?
Symptom relief TerminatedThis study looked at whether adding a nerve block given by the surgeon to standard pain injections around the knee can improve pain control after total knee replacement. The trial included 93 adults with osteoarthritis who were having their first knee replacement. The goal was to…
Matched conditions: OSTEOARTHRITIS
Phase: PHASE2, PHASE3 • Sponsor: OrthoCarolina Research Institute, Inc. • Aim: Symptom relief
Last updated May 26, 2026 07:26 UTC
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Laser light tested to ease hand arthritis pain in military members
Symptom relief TerminatedThis study looked at whether low level laser therapy (LLLT) can reduce pain and improve hand function in people with hand osteoarthritis. About 83 military members and their families were to receive either real LLLT or a sham treatment once a week for six weeks. The study was ter…
Matched conditions: OSTEOARTHRITIS
Phase: NA • Sponsor: David Moss • Aim: Symptom relief
Last updated May 18, 2026 12:11 UTC
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Tiny nerve zapper eases knee pain without surgery?
Symptom relief TerminatedThis study tested a temporary device that stimulates nerves around the knee to relieve chronic pain from osteoarthritis. Twelve adults with knee pain received the treatment, and researchers measured changes in pain intensity and quality of life. The goal was to see if this non-su…
Matched conditions: OSTEOARTHRITIS
Sponsor: Wake Forest University Health Sciences • Aim: Symptom relief
Last updated May 18, 2026 11:59 UTC
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Custom knee implants put to the test against standard models
Knowledge-focused TerminatedThis study looked at 215 people with osteoarthritis who had knee replacement surgery. It compared a custom-made knee implant (ConforMIS iTotal) with standard off-the-shelf implants to see which one helped patients move and function better. The study was stopped early, but the goa…
Matched conditions: OSTEOARTHRITIS
Phase: NA • Sponsor: Restor3D • Aim: Knowledge-focused
Last updated May 22, 2026 13:53 UTC
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Hip implant movement study stopped early
Knowledge-focused TerminatedThis study looked at how much a specific hip implant (the Pinnacle shell) moves in the body during the first two years after surgery. Researchers used special X-ray techniques to measure this movement in 100 people getting hip replacements for arthritis. The study was terminated …
Matched conditions: OSTEOARTHRITIS
Phase: NA • Sponsor: DePuy Orthopaedics • Aim: Knowledge-focused
Last updated May 19, 2026 12:00 UTC