IRRITABLE BOWEL SYNDROME

This study tested a non-invasive brain stimulation technique called rTMS to see if it could reduce chronic visceral pain in people with irritable bowel syndrome with diarrhea (IBS-D). Researchers used brain scans to find overactive pain areas and then targeted them with magnetic …

This study tested whether adding probiotic supplements to the standard antibiotic treatment (rifaximin) helps people with SIBO feel better. 129 adults with SIBO took either probiotics or a placebo for 3 months while also following a special diet. The main goals were to see if pro…

This study tested a simple, non-instrumental biofeedback technique to reduce abdominal bloating in people with Irritable Bowel Syndrome (IBS) or functional dyspepsia. 41 participants were taught exercises to control their belly and chest muscles using a video, or received a place…

This study tested whether a standardized Boswellia extract (a herbal supplement) combined with patient education could improve symptoms of Irritable Bowel Syndrome (IBS). Sixty adults with moderate IBS took the extract twice daily for 30 days and attended educational sessions. Re…

This study tested whether ethosuximide, a drug used for seizures, can reduce belly pain in people with irritable bowel syndrome (IBS). 162 adults with IBS took part. The goal was to see if the drug lowers pain and improves quality of life. The study is complete, and results may o…

This study tested three different eating plans in 135 adults with irritable bowel syndrome with diarrhea (IBS-D) to see which best reduces stomach pain, bloating, and other symptoms. Participants followed either a low FODMAP diet, a diet using Tritordeum (a type of wheat) foods, …

This study tested whether rimegepant, a drug used for migraines, can reduce chronic abdominal pain in people with irritable bowel syndrome (IBS). 39 adults with non-constipation IBS took the medicine and reported their pain levels daily. The goal was to see if the drug could ease…

This small pilot study looked at whether varenicline, a drug used to help people stop smoking, can change how the rectum senses pressure in people with irritable bowel syndrome (IBS) who have chronic belly pain but not constipation. Eight adults took the drug and had balloon test…

This study tested a daily synbiotic supplement (a mix of probiotics and prebiotics) in 48 adults with irritable bowel syndrome (IBS) to see if it was safe and improved gut health. Participants took either the supplement or a placebo for 12 weeks. The main goal was to check for si…

This study looked at whether indoor physical activity can improve symptoms in people with both fibromyalgia (a condition causing widespread pain and fatigue) and irritable bowel syndrome (IBS). Researchers measured changes in gut health, pain, and psychological well-being in 165 …

This study tested whether a new diet called the 5Ad diet works as well as the well-known low FODMAP diet for reducing stomach symptoms like pain, bloating, and gas. 52 adults with irritable bowel syndrome or food intolerances tried both diets for one week each. The goal was to se…

This study looked at whether a home-based audio program of gut-directed hypnotherapy could help children aged 8-18 with irritable bowel syndrome or functional abdominal pain. The goal was to see if it could improve sleep quality and reduce belly pain. Participants either did the …

This study looked at whether cutting out certain carbs (FODMAPs) can reduce ongoing stomach issues in people with celiac disease who already follow a strict gluten-free diet. Researchers surveyed and then ran a controlled trial with 80 adults. The goal was to see if a low FODMAP …

This small pilot study tested whether a device that gently stimulates a nerve in the ear (the vagus nerve) could help women with Irritable Bowel Syndrome (IBS). Ten to eighteen women used the device daily for six months. Researchers measured changes in symptoms, digestion, and qu…

This study tested whether an online service that provides personalized Low-FODMAP menus and nutritional support can improve quality of life and control symptoms in people with irritable bowel syndrome (IBS). Forty adults with IBS followed the diet using a web platform for 6 month…

This study tested whether a smartphone app called Zemedy can improve quality of life for adults with Irritable Bowel Syndrome (IBS). Over 450 participants used either Zemedy or a relaxation training app. The goal was to see if the app helps reduce IBS symptoms and related distres…

This study looked at different treatments for vestibulodynia, a long-term pain condition affecting the vulva that impacts the lives of about 1 in 6 women. Researchers tested a pain cream, an oral medication, and a combination of both against a placebo in 209 women aged 18-50. The…

This study looked at whether a simple breath test can help identify which people with diarrhea-predominant irritable bowel syndrome (IBS-D) are more likely to get relief from the antibiotic rifaximin. 148 adults with IBS-D took the breath test and then received rifaximin treatmen…

This study looked at whether a diet low in FODMAPs (certain carbohydrates) can ease symptoms of Irritable Bowel Syndrome (IBS). Researchers tested 112 adults with IBS to see if a fructose breath test could predict who would benefit from the diet. The goal was to find a simple way…

This study looked at whether sleep problems like insomnia are linked to a lower pain threshold in the gut for people with Irritable Bowel Syndrome (IBS). Researchers measured pain sensitivity using a balloon-like device in 70 adults, including those with IBS, insomnia, both, or n…

This study looked at whether gluten or whole wheat causes stomach issues in people with Irritable Bowel Syndrome (IBS). 29 adults who felt better on a gluten-free diet were given snack bars with either purified gluten, whole wheat (gluten plus other proteins), or a gluten-free pl…

This study looked at why certain foods trigger symptoms in people with Irritable Bowel Syndrome (IBS). Researchers focused on how gut bacteria produce histamine when digesting specific carbohydrates (FODMAPs). Thirty adults with IBS followed a low-FODMAP diet and took special dri…

This study looked at 163 children aged 7-12 with chronic abdominal pain to see if simple tests (biomarkers) could predict whether they would benefit more from cognitive behavioral therapy (CBT) or a low FODMAP diet. The goal was to personalize treatment and improve symptom relief…

This study looked at whether IBS symptoms come back depending on the dose of certain FODMAPs (mannitol and fructans) after a successful low-FODMAP diet. 45 adults with IBS took part in a blinded test where they received increasing doses of these FODMAPs to find the amount that tr…

This study looked at how FODMAPs (certain carbohydrates that can cause gas and bloating) directly affect movement in the large intestine. Fifteen healthy volunteers each had three colonoscopies to measure colon pressure and receive FODMAP infusions. The goal was to understand the…