Can enzyme pills beat the bloat? new study tests a simple fix for IBS sufferers
NCT ID NCT07465562
First seen Mar 18, 2026 · Last updated Jun 22, 2026 · Updated 12 times
Summary
This study tested whether a dietary supplement containing digestive enzymes (Galactol®) could reduce bloating after meals in people with irritable bowel syndrome (IBS). 300 adults were randomly assigned to take the enzyme supplement plus a low-FODMAP diet, or just the diet alone, for 14 days. The main goal was to see if bloating intensity improved more with the supplement.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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University of Urbino Carlo Bo
Urbino, 61029, Italy
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
digestive enzyme supplement (alpha-galactosidase, beta-galactosidase, prolyl-endopeptidase)
What this could lead to
If it works, this could offer a simple, over-the-counter option to ease bloating after meals for people with IBS.
What could go wrong
This is a small, short-term study (14 days) with no blinding, so results may be influenced by placebo effects. The supplement is tested alongside a special diet, so it's unclear if the supplement alone would help.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.