DOWN SYNDROME

This study tested whether the drug tofacitinib is safe and effective for treating several common autoimmune skin conditions in adolescents and adults with Down syndrome. Researchers wanted to see if reducing overactive immune signaling could improve skin health, quality of life, …

This study tested whether dilating the eyes (using drops to widen the pupil) gives a better measurement for glasses prescriptions in people with Down syndrome. People with Down syndrome often have unique eye shapes that make standard vision tests less accurate. Researchers compar…

This study tested whether a simple blood test from the mother could safely replace invasive procedures for detecting Down syndrome. Researchers compared the new blood test against standard invasive tests in over 2,000 pregnant women at higher risk. The goal was to see if the bloo…

This study tested whether a 12-week program of online group dance classes is a practical and acceptable way to help young adults with Down syndrome get more active. Because over 90% of people with Down syndrome develop Alzheimer's disease, and physical activity may help delay its…

This study compared two different approaches—orofacial therapy and therapeutic yoga—to see which might better help children with Down syndrome. Thirty children, aged 5 to 12, participated. Researchers measured improvements in swallowing, sleep habits, and overall quality of life …

This study tested whether a specific diet plan combined with nutritional supplements could help improve thinking skills, sleep quality, and body function in children and young adults with Down syndrome, autism, or ADHD. It involved 76 participants aged 2 to 35 who followed the pr…

This study aimed to understand why parents in Reunion Island, a French territory, rarely choose to end a pregnancy after learning their baby has Down Syndrome. Researchers interviewed 28 mothers and fathers who had a child with Down Syndrome to learn about their beliefs, values, …

This study aimed to understand why people with Down syndrome often have very low fitness levels and find exercise difficult. Researchers tested whether a 12-week supervised exercise program could improve how the body regulates blood flow to the heart and muscles during activity. …

This study aimed to understand if specific movement practice helps babies with Down syndrome develop thinking and language skills. Researchers worked with 51 infants, having some practice walking on a small treadmill or using special mittens for grasping. They measured developmen…

This study created a new survey tool to measure health in people with Down syndrome, since existing tools don't work well for this population. Researchers worked with 542 caregivers of people with Down syndrome to develop and test the survey. The goal is to create a reliable way …

This study adapted a Turkish version of a trunk control assessment scale for infants with Down syndrome. Researchers tested the tool's accuracy and consistency in measuring how well babies control their torso during sitting and movement. The goal is to help therapists better trac…

This study aimed to find signs that could help doctors predict and diagnose sleep apnea earlier in people with Down syndrome. Researchers studied 40 adults with Down syndrome, looking at factors like facial structure, physical activity levels, and heart function during sleep. The…

This study explored whether specific training could improve spatial thinking skills—like mentally rotating objects or understanding different viewpoints—in people with Down syndrome. Researchers worked with 84 participants, including adolescents and young adults with Down syndrom…

This study tested whether an 8-week online nutrition education program could improve eating habits for people with Down syndrome and increase their caregivers' nutrition knowledge. It involved 31 individuals with Down syndrome and their 31 caregivers in Turkey. Researchers measur…