COLON CANCER

This study tested a combination of three drugs (encorafenib, binimetinib, and cetuximab) given before surgery to people with a specific type of colorectal cancer that has a BRAF V600E mutation. Only 2 patients took part, and the main goal was to see how much the tumor shrank afte…

This study looked at whether taking vitamin D and aspirin daily, along with exercise and a low-fat diet, could lower the chance of colorectal cancer returning in people who had already been treated. It involved 16 adults with no visible cancer but with tiny bits of cancer DNA in …

This study tested an experimental drug called CTX-009 in 49 adults with metastatic colorectal cancer that had worsened after two or three prior chemotherapy treatments. The goal was to see if the drug could shrink tumors or stop them from growing. The trial is now complete, and r…

This pilot study tested whether mindfulness training could reduce chronic stress and related colon cancer risk factors in Black women aged 45-65 who live in high-crime Chicago neighborhoods and have had a past colon polyp. 24 women participated. The goal was to see if the program…

This study tested a combination of two drugs, palbociclib and cetuximab, in 24 people with a specific type of advanced colon cancer that had spread. The goal was to see if the combination could shrink or stop the growth of tumors. The study found that the treatment helped control…

This study tested a new treatment for people with advanced gastrointestinal cancers (like stomach, colon, or pancreatic cancer) that had spread and stopped responding to standard therapy. Doctors took immune cells from each patient's tumor, used CRISPR gene editing to remove a ge…

This study looked at 200 adults having elective colorectal surgery for conditions like colon cancer or diverticulitis. It compared two pain relief methods: a TAP block (injection into the abdominal wall) versus epidural anesthesia (injection near the spine). The goal was to see w…

This study looked at whether a supervised exercise program can help people with breast or colon cancer feel better and have a better quality of life. 78 patients took part, some also receiving chemotherapy, radiation, or hormone therapy. The exercise group did supervised workouts…

This study looked at 320 men to find out if a digital rectal exam works better when the patient lies on their side or on their back. The goal was to see which position lets the doctor check the full rectum more easily. The results help doctors choose the best way to perform this …

This study compared text message reminders to standard phone call reminders for getting people to complete a home stool test (FIT) for colon cancer screening. Over 1,200 adults from NYU family health centers took part. The goal was to see if texting could increase the number of p…

This study looked at 1,471 people with colon cancer to see if their tumor's DNA repair status (called MMR) affects how cancer spreads to lymph nodes and overall survival. Researchers compared two groups—those with normal repair (pMMR) and those with faulty repair (dMMR)—to find p…

This study tested a new AI system called EndoStyle that can change the style of colonoscopy images to look like they came from different types of equipment. 40 doctors with colonoscopy experience were shown real and AI-transformed images to see if they could tell the difference. …