AMPUTATION

This study tested a new way of coordinating care for rural patients with diabetic foot ulcers, who are at higher risk of major leg amputation. The goal was to connect them more quickly with specialists to reduce the need for above-ankle amputations. The study involved 131 partici…

This study looked at whether adding the antibiotic rifampin to usual treatment can help diabetic patients with serious foot bone infections avoid amputation. Over 800 veterans took part. The goal was to see if the combination works better than standard care alone.

This study tested a new type of bionic leg for people with below-knee amputations. The leg uses special surgical connections to muscles, allowing users to control ankle movements more naturally and even feel the leg's position. 14 active amputees participated, and the goal was to…

This study tested a new type of prosthetic leg for people who have lost a leg below or above the knee. The smart leg uses sensors to detect the user's movements and provides active help at the knee and ankle to make walking smoother and more natural. Eight experienced prosthetic …

This study tested hand transplants in 7 people who lost both forearms. The goal was to see if the brain can adapt to the new hands and improve daily life. Participants had to be between 20 and 40 years old and had to have had their amputation 3 months to 3 years before the transp…

This study tested a special vacuum dressing called PREVENA on 272 adults who had a leg amputated. The goal was to see if it could reduce wound problems like infection, fluid buildup, or skin reopening. Participants were randomly assigned to get either the special dressing or stan…

This study tested whether injecting donor stem cells into the leg muscles of people undergoing major leg amputation could prevent wound complications and reduce the need for further amputations. 81 adults aged 40-90 with severe artery disease received stem cell injections above a…

This study tested a Turkish version of the Johns Hopkins In-Room Independence Scale, which measures a patient's ability to move, use the toilet, and think clearly while in their hospital room. The goal was to help doctors and nurses better understand a patient's fall risk and car…

This study tested a new digital system that creates prosthetic sockets while the person stands, aiming for a better fit than traditional methods. Ten adults with below-knee amputations tried both socket types. Researchers measured skin health and blood flow to see if the new appr…

This study tested whether a medicated cloth (glycopyrronium) can reduce excessive sweating at the amputation site in people with limb loss. Thirteen participants used either the active cloth or a placebo for four weeks, then switched after a break. The goal was to see if less swe…

This study tested a new prosthetic foot, the PRO-FLEX PIVOT, against a standard energy-storing foot in 30 people with a leg amputation below the knee. The goal was to see if the new foot improves mobility and comfort. Participants tried both feet and reported their walking abilit…

This study tested whether adjustable prosthetic sockets are more comfortable and improve mobility compared to standard sockets. Twenty-nine adults with a leg amputation tried both types. Researchers measured comfort, balance, walking speed, and quality of life to see which socket…

This study tested a new microprocessor-controlled prosthetic knee in 11 active adults with leg amputations. Participants used the new knee for 4 weeks at home, and researchers measured satisfaction with stairs, ramps, and walking, as well as mobility and balance. The goal was to …

This study tested a new body-powered prosthetic hook designed to improve grasping for people with upper limb loss. Eight adults aged 18-80 with amputations compared the new device to standard hooks by performing everyday tasks. The goal was to see if the new hook works better and…

This study tested a new powered knee (Mobili Knee) in 6 people with leg amputations. Participants did walking and balance tests with their usual knee and then with the new knee. The goal was to see if the powered knee improves mobility and reduces fall risk.

This study tested a new microprocessor-controlled prosthetic knee in 14 people with leg amputations who already use a similar bionic knee. The goal was to see if the new knee improved satisfaction when walking downstairs and overall mobility. Participants tried the new knee and t…

This study tested a new powered prosthetic knee (Power Knee) in 17 adults with a leg amputation above the knee. Participants tried both the Power Knee and their usual knee to compare how much effort they felt when walking. The goal was to see if the powered knee reduces exertion …

This study looked at 13 people with one leg amputation to find which prosthetic foot helps them walk best while carrying infants, toddlers, or other loads. Researchers measured how well each foot supported body weight, helped with forward movement, and kept balance. The goal is t…

This study looked at whether prosthetists (the professionals who fit artificial limbs) can screen for common health problems that often go unnoticed after a leg amputation, such as poor blood flow, nerve damage, depression, and back pain. 70 adults with a below- or above-knee amp…

This observational study looked at 26 adults—some with a below-knee amputation and some without—to see how core function and endurance relate to balance, walking speed, and body awareness. Participants performed tests of core strength, balance, and joint position sense. The goal …

This study looked at how satisfied people in Gaza who use a lower limb prosthesis are with their device and their quality of life during the 2023 war. Researchers surveyed 128 adults who had used a prosthesis for at least six months. The goal was to understand their needs and hel…

This study looked at how people with leg amputations (below or above the knee) use their muscles and adjust their body to stay balanced when the surface they stand on moves suddenly. 29 adults aged 18-45 who had used a prosthetic leg for at least a year took part. The goal was to…

This study investigates why humans swing their arms when walking, a common but poorly understood movement. Researchers observed 25 people, including healthy volunteers and those with conditions like multiple sclerosis or stroke, walking on a special treadmill. The goal is to lear…

This study tested a new type of pump that creates a vacuum to help hold a prosthetic limb in place. Twelve people with amputations walked in a lab to see if the pump worked well. The goal was to improve comfort and mobility for prosthetic users.

This study tested a new way to perform lower leg amputations that could help people use advanced prosthetic limbs more naturally. Researchers worked with 50 adults who needed an amputation due to injury, birth defects, or arthritis. The goal was to see if the new surgical method …

This study looked at how powered ankle prostheses change the pressure inside the prosthetic socket and the health of the residual limb in people with below-knee amputations. Six adults who already use a standard prosthetic leg walked on level ground while researchers measured soc…

This study looked at how well a low-cost prosthetic foot works compared to standard ones for people who have lost a leg below the knee. Six participants performed balance tests, walking tasks, and jumps in a lab. The goal was to see if the cheaper option could provide similar mov…

This study tested a new type of prosthetic foot designed for people with below-knee amputation who have longer residual limbs. The foot is low-profile but aims to provide better flexibility and energy return, similar to taller prosthetic feet. Six adults who already use a low-pro…