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Respiratory system disorder
MONDO:0005087A non-neoplastic or neoplastic disorder that affects the respiratory system. Representative examples include pneumonia, chronic obstructive pulmonary disease, pulmonary failure, lung adenoma, lung carcinoma, and tracheal carcinoma.
Also known as: disease of respiratory system, disease or disorder of respiratory system, disorder of respiratory system, respiratory disease, respiratory disorder, respiratory system disease, respiratory system disease or disorder, respiratory system disorder
10874 clinical trials for this condition and its sub-types, 150 tagged with Respiratory system disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Respiratory system disorder
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Lower respiratory tract disorder 18 trials · 7,952 incl. sub-types
5 sub-types
- Lung disorder 251 trials · 7,091 incl. sub-types Sub-types →
- Tracheal disorder 6 trials · 1,091 incl. sub-types Sub-types →
- Bronchial disorder 19 trials · 1,012 incl. sub-types Sub-types →
- Pleural disorder 15 trials · 177 incl. sub-types Sub-types →
- Tracheobronchitis 5 trials · 55 incl. sub-types Sub-types →
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Respiratory system cancer 6 trials · 4,524 incl. sub-types
9 sub-types
- Lung cancer 1,212 trials · 3,948 incl. sub-types Sub-types →
- Pharynx cancer 10 trials · 497 incl. sub-types Sub-types →
- Larynx cancer 41 trials · 125 incl. sub-types Sub-types →
- Pleural cancer 9 trials · 83 incl. sub-types Sub-types →
- Bronchus cancer 3 trials · 26 incl. sub-types Sub-types →
- Paranasal sinus cancer 4 trials · 24 incl. sub-types Sub-types →
- Nasal cavity cancer 5 trials · 14 incl. sub-types Sub-types →
- SMARCA4-deficient sarcoma of thorax 8 trials
- Tracheal cancer 0 trials · 1 incl. sub-types Sub-types →
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Respiratory tract neoplasm 32 trials · 4,444 incl. sub-types
8 sub-types
- Lung neoplasm 1,371 trials · 4,046 incl. sub-types Sub-types →
- Nasopharyngeal neoplasm 37 trials · 226 incl. sub-types Sub-types →
- Laryngeal neoplasm 72 trials · 138 incl. sub-types Sub-types →
- Pleural neoplasm 5 trials · 97 incl. sub-types Sub-types →
- Bronchial neoplasm 20 trials · 38 incl. sub-types Sub-types →
- Nasal cavity neoplasm 1 trial · 15 incl. sub-types Sub-types →
- SMARCA4-deficient sarcoma of thorax 8 trials
- Trachea neoplasm 2 trials · 5 incl. sub-types Sub-types →
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Upper respiratory tract disorder 5 trials · 1,854 incl. sub-types
10 sub-types
- Tracheal disorder 6 trials · 1,091 incl. sub-types Sub-types →
- Nasopharyngeal disorder 1 trial · 263 incl. sub-types Sub-types →
- Laryngeal disorder 44 trials · 259 incl. sub-types Sub-types →
- Nasal cavity disorder 3 trials · 226 incl. sub-types Sub-types →
- Pharyngitis 34 trials · 43 incl. sub-types Sub-types →
- Tonsillitis 23 trials · 28 incl. sub-types Sub-types →
- Adenoid hypertrophy 23 trials
- Epiglottitis 1 trial Sub-types →
- Acute laryngopharyngitis 0 trials
- Uvulitis 0 trials
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Respiratory tract infectious disorder 176 trials · 1,334 incl. sub-types
14 sub-types
- Pneumonia 327 trials · 611 incl. sub-types Sub-types →
- Viral respiratory tract infection 47 trials · 566 incl. sub-types Sub-types →
- Fungal lung infectious disease 6 trials · 57 incl. sub-types Sub-types →
- Pulmonary non-tuberculous mycobacterial infection 48 trials
- Streptococcal sore throat 8 trials
- Pleural tuberculosis 7 trials Sub-types →
- Tracheitis 2 trials · 7 incl. sub-types Sub-types →
- Lung abscess 3 trials
- Pneumonic plague 3 trials
- Tuberculous fibrosis of lung 3 trials
- Laryngeal diphtheria 0 trials
- Laryngeal tuberculosis 0 trials
- Nasopharyngeal diphtheria 0 trials
- Silicotuberculosis 0 trials
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Sleep apnea syndrome 214 trials · 603 incl. sub-types
2 sub-types
- Obstructive sleep apnea syndrome 519 trials · 520 incl. sub-types Sub-types →
- Central sleep apnea syndrome 21 trials · 23 incl. sub-types Sub-types →
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Disorder of pharynx 3 trials · 598 incl. sub-types
10 sub-types
- Pharynx cancer 10 trials · 497 incl. sub-types Sub-types →
- Neoplasm of oropharynx 3 trials · 280 incl. sub-types Sub-types →
- Nasopharyngeal disorder 1 trial · 263 incl. sub-types Sub-types →
- Neoplasm of hypopharynx 0 trials · 100 incl. sub-types Sub-types →
- Tonsillitis 23 trials · 28 incl. sub-types Sub-types →
- Takayasu arteritis 27 trials
- Tonsil neoplasm 0 trials · 8 incl. sub-types Sub-types →
- Peritonsillar abscess 4 trials
- Epiglottitis 1 trial Sub-types →
- Oropharyngeal anthrax 0 trials
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Cystic fibrosis 285 trials
1 sub-type
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Allergic respiratory disease 2 trials · 220 incl. sub-types
4 sub-types
- Allergic rhinitis 97 trials · 142 incl. sub-types Sub-types →
- Allergic asthma 41 trials Sub-types →
- Hypersensitivity pneumonitis 25 trials · 30 incl. sub-types Sub-types →
- Allergic bronchopulmonary aspergillosis 15 trials Sub-types →
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Paranasal sinus disorder 12 trials · 163 incl. sub-types
7 sub-types
- Sinusitis 44 trials · 131 incl. sub-types Sub-types →
- Paranasal sinus neoplasm 5 trials · 29 incl. sub-types Sub-types →
- Maxillary sinus cholesteatoma 0 trials
- Polyp of ethmoidal sinus 0 trials
- Polyp of frontal sinus 0 trials
- Polyp of maxillary sinus 0 trials
- Polyp of sphenoidal sinus 0 trials
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Perinatal asphyxia 153 trials
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Pulmonary tuberculosis 108 trials · 111 incl. sub-types
3 sub-types
- Tuberculous fibrosis of lung 3 trials
- Primary pulmonary tuberculosis 0 trials
- Silicotuberculosis 0 trials
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Bronchopulmonary dysplasia 96 trials
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Diaphragm disorder 27 trials · 91 incl. sub-types
5 sub-types
- Congenital diaphragmatic hernia 45 trials Sub-types →
- Respiratory paralysis 20 trials
- Diaphragmatic eventration 3 trials
- Diaphragmatic malformation 1 trial
- Diaphragmitis 0 trials
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Altitude sickness 54 trials · 56 incl. sub-types
2 sub-types
- Acute mountain sickness 7 trials
- Chronic mountain sickness 3 trials
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Alpha 1-antitrypsin deficiency 44 trials
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Pertussis 39 trials
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Primary ciliary dyskinesia 34 trials
59 sub-types
- Primary ciliary dyskinesia 1 6 trials
- CFAP46-related primary ciliary dyskinesia 0 trials
- Stromme syndrome 0 trials
- Ciliary discoordination due to random ciliary orientation 0 trials
- Ciliary dyskinesia with defective radial spokes 0 trials
- Ciliary dyskinesia with excessively long cilia 0 trials
- Ciliary dyskinesia with transposition of ciliary microtubules 0 trials
- Ciliary dyskinesia, primary, 36, X-linked 0 trials
- Ciliary dyskinesia, primary, 37 0 trials
- Ciliary dyskinesia, primary, 38 0 trials
- Ciliary dyskinesia, primary, 39 0 trials
- Ciliary dyskinesia, primary, 40 0 trials
- Ciliary dyskinesia, primary, 41 0 trials
- Ciliary dyskinesia, primary, 42 0 trials
- Ciliary dyskinesia, primary, 43 0 trials
- Ciliary dyskinesia, primary, 44 0 trials
- Ciliary dyskinesia, primary, 45 0 trials
- Ciliary dyskinesia, primary, 46 0 trials
- Ciliary dyskinesia, primary, 47, and lissencephaly 0 trials
- Ciliary dyskinesia, primary, 48, without situs inversus 0 trials
- Ciliary dyskinesia, primary, 49, without situs inversus 0 trials
- Ciliary dyskinesia, primary, 50 0 trials
- Ciliary dyskinesia, primary, 51 0 trials
- Ciliary dyskinesia, primary, 52 0 trials
- Ciliary dyskinesia, primary, 53 0 trials
- Ciliary dyskinesia, primary, 54 0 trials
- Primary ciliary dyskinesia 10 0 trials
- Primary ciliary dyskinesia 11 0 trials
- Primary ciliary dyskinesia 12 0 trials
- Primary ciliary dyskinesia 13 0 trials
- Primary ciliary dyskinesia 14 0 trials
- Primary ciliary dyskinesia 15 0 trials
- Primary ciliary dyskinesia 16 0 trials
- Primary ciliary dyskinesia 17 0 trials
- Primary ciliary dyskinesia 18 0 trials
- Primary ciliary dyskinesia 19 0 trials
- Primary ciliary dyskinesia 2 0 trials
- Primary ciliary dyskinesia 20 0 trials
- Primary ciliary dyskinesia 21 0 trials
- Primary ciliary dyskinesia 22 0 trials
- Primary ciliary dyskinesia 23 0 trials
- Primary ciliary dyskinesia 24 0 trials
- Primary ciliary dyskinesia 25 0 trials
- Primary ciliary dyskinesia 26 0 trials
- Primary ciliary dyskinesia 27 0 trials
- Primary ciliary dyskinesia 28 0 trials
- Primary ciliary dyskinesia 29 0 trials
- Primary ciliary dyskinesia 3 0 trials
- Primary ciliary dyskinesia 30 0 trials
- Primary ciliary dyskinesia 32 0 trials
- Primary ciliary dyskinesia 33 0 trials
- Primary ciliary dyskinesia 34 0 trials
- Primary ciliary dyskinesia 35 0 trials
- Primary ciliary dyskinesia 4 0 trials
- Primary ciliary dyskinesia 5 0 trials
- Primary ciliary dyskinesia 6 0 trials
- Primary ciliary dyskinesia 7 0 trials
- Primary ciliary dyskinesia 8 0 trials
- Primary ciliary dyskinesia 9 0 trials
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Severe acute respiratory syndrome 30 trials
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Infantile apnea 5 trials · 22 incl. sub-types
1 sub-type
- Apnea of prematurity 20 trials
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Recurrent respiratory papillomatosis 8 trials · 9 incl. sub-types
1 sub-type
- Laryngeal papillomatosis 1 trial
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Respiratory system benign neoplasm 1 trial · 8 incl. sub-types
15 sub-types
- Benign laryngeal neoplasm 1 trial · 2 incl. sub-types Sub-types →
- Benign neoplasm of trachea 0 trials · 2 incl. sub-types Sub-types →
- Lung benign neoplasm 1 trial · 2 incl. sub-types Sub-types →
- Benign neoplasm of nasal cavity 1 trial Sub-types →
- Benign neoplasm of ethmoidal sinus 0 trials Sub-types →
- Benign neoplasm of frontal sinus 0 trials Sub-types →
- Benign neoplasm of hypopharynx 0 trials Sub-types →
- Benign neoplasm of maxillary sinus 0 trials Sub-types →
- Benign neoplasm of nasopharynx 0 trials
- Benign neoplasm of oropharynx 0 trials
- Benign neoplasm of pleura 0 trials Sub-types →
- Benign neoplasm of sphenoidal sinus 0 trials Sub-types →
- Benign neoplasm of tonsil 0 trials Sub-types →
- Endobronchial lipoma 0 trials
- Paranasal sinus Schneiderian papilloma 0 trials Sub-types →
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Respiratory or thoracic malformation 0 trials · 8 incl. sub-types
1 sub-type
- Thoracic malformation 1 trial · 8 incl. sub-types Sub-types →
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Pulmonary hypoplasia 7 trials
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Reactive airway disease 5 trials
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2 sub-types
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5 sub-types
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Young syndrome 2 trials
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Diffuse alveolar hemorrhage 2 trials
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Plastic bronchitis 2 trials
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Middle East respiratory syndrome 1 trial
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Bronchogenic cyst 1 trial
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3 sub-types
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16q24.1 microdeletion syndrome 0 trials
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IgG4-related mediastinitis 0 trials
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Mounier-Kuhn syndrome 0 trials
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Siegler-Brewer-Carey syndrome 0 trials
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Williams-Campbell syndrome 0 trials
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Acinar dysplasia 0 trials
3 sub-types
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Bronchiectasis and nasal polyposis 0 trials
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Congenital bronchobiliary fistula 0 trials
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Eosinophilic granuloma 0 trials
1 sub-type
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Isolated left bronchial isomerism 0 trials
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Laryngo-onycho-cutaneous syndrome 0 trials
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Mucopolysaccharidosis-plus syndrome 0 trials
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Pulmonary agenesis 0 trials
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Staphylococcal necrotizing pneumonia 0 trials
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Tracheal agenesis 0 trials
Most studied deeper sub-types
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New COVID shot tested in vulnerable kids
Vaccine CompletedThis Phase 3 trial tests an updated COVID-19 vaccine (BNT162b2, 2025/2026 formulation) in 343 children aged 5 to 11 who have medical conditions that put them at high risk for severe COVID-19. All participants receive one dose and are monitored for about 6 months to check safety a…
Phase 3 • Sponsor: BioNTech SE • Aim: Vaccine
Last updated Aug 09, 2026 00:00 UTC
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New bird flu booster shot shows promise in early trial
Vaccine CompletedThis study tested a booster vaccine for H5N6 bird flu in about 260 adults. Some had previously received an H5N1 bird flu vaccine, while others had not. The goal was to see if the booster was safe and triggered a strong immune response. Participants received one or two doses of th…
Phase 2 • Sponsor: Seqirus • Aim: Vaccine
Last updated Jun 27, 2026 12:33 UTC
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Can an antibody injection shrink nasal polyps?
Disease control CompletedResearchers are testing an experimental antibody drug called verekitug in adults with chronic rhinosinusitis with nasal polyps, a condition where inflamed tissue grows inside the nasal passages and causes congestion. Participants receive either verekitug or a placebo injection wh…
Phase 2 • Sponsor: Upstream Bio Inc. • Aim: Disease control
Last updated Sep 20, 2026 00:00 UTC
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Can a drug that calms inflammation ease chronic sinusitis?
Disease control CompletedThis trial tests whether dupilumab, an injectable drug that blocks certain inflammatory signals, can reduce sinus swelling and improve symptoms like loss of smell and runny nose in adults with chronic sinusitis who do not have nasal polyps. Participants receive either dupilumab o…
Phase 2 • Sponsor: Sanofi • Aim: Disease control
Last updated Aug 01, 2026 00:00 UTC
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Video chats boost asthma med adherence in young patients
Disease control CompletedThis study tested whether video-based medication coaching helps adolescents and young adults with uncontrolled asthma take their inhaled steroids more regularly. 375 participants received either standard care or telehealth sessions to improve medication use. The goal was to see i…
Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC
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New PAH pill aims to delay worsening in large trial
Disease control CompletedThis study tested a new oral drug called ralinepag in 687 adults with pulmonary arterial hypertension (PAH), a serious lung condition that makes the heart work harder. Participants took ralinepag or a placebo on top of their usual PAH medications. The main goal was to see if rali…
Phase 3 • Sponsor: United Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New drug verekitug aims to curb severe asthma attacks
Disease control CompletedThis study tested a new drug called verekitug (UPB-101) in 479 adults with severe asthma. The goal was to see if it could reduce asthma attacks and improve lung function compared to a placebo. Participants received either verekitug or a dummy injection over several months. The tr…
Phase 2 • Sponsor: Upstream Bio Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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Can a lung drug stop COVID scarring?
Disease control CompletedThis study tested whether nintedanib, a drug used for other lung diseases, can slow down lung damage in people who had severe COVID-19. It included 103 adults who still had lung problems more than 30 days after their COVID diagnosis. The main goal was to see if the drug helped ma…
Phase 4 • Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Disease control
Last updated Jun 27, 2026 12:26 UTC
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New drug cocktail targets tough lung cancer mutation
Disease control CompletedThis phase 2 trial tested a combination of two oral drugs, RMC-4630 and sotorasib, in 47 adults with advanced KRASG12C-mutant non-small cell lung cancer that had progressed after standard treatments. The goal was to see if the combination could shrink tumors. The study is now com…
Phase 2 • Sponsor: Revolution Medicines, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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New shot method for Alpha-1 lung disease shows promise in early trial
Disease control CompletedThis study tested a new way to give Alpha-1 protein therapy by injecting it under the skin instead of into a vein. Seventeen adults with Alpha-1 Antitrypsin Deficiency received either a low or high dose weekly for eight weeks. The main goal was to check safety and how the drug mo…
Phase 1/2 • Sponsor: Grifols Therapeutics LLC • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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New pill for scarred lungs shows promise in early trial
Disease control CompletedThis study tested an experimental oral drug called INS018_055 in 71 adults with idiopathic pulmonary fibrosis (IPF), a disease that causes lung scarring and makes breathing hard. The main goal was to see if the drug is safe and tolerable over 12 weeks compared to a placebo. Resea…
Phase 2 • Sponsor: InSilico Medicine Hong Kong Limited • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Could a cold virus drug prevent COPD Flare-Ups?
Disease control CompletedThis study tested whether the drug vapendavir can reduce breathing problems in people with COPD who catch a rhinovirus (common cold). Fifty-two adults with COPD were given either vapendavir or a placebo after being exposed to the virus. The main goal was to see if vapendavir lowe…
Phase 2 • Sponsor: Altesa Biosciences, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Daily vitamin d may slash lung risks in kids with sickle cell disease
Disease control CompletedThis study tested whether taking vitamin D every day could reduce lung complications in children and teens with sickle cell disease. Lung problems like infections, asthma attacks, and acute chest syndrome are major causes of illness and death in this condition. Researchers gave d…
Phase 2 • Sponsor: Columbia University • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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New pill shows promise against lung cancer brain metastases
Disease control CompletedThis study tested a new drug called AZD3759 against standard targeted therapies (erlotinib or gefitinib) in 492 people with advanced EGFR-mutant lung cancer that had spread to the brain. The goal was to see if AZD3759, which is designed to better reach the brain, could keep the c…
Phase 2/3 • Sponsor: Alpha Biopharma (Jiangsu) Co., Ltd. • Aim: Disease control
Last updated Jun 26, 2026 16:13 UTC
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Simple blood test could slash antibiotic overuse for coughs and colds
Diagnosis CompletedThis study tested whether giving general practitioners a rapid C-reactive protein (CRP) test helps them decide when antibiotics are truly needed for patients with respiratory infections. 140 patients with symptoms like cough, fever, or sore throat took part. Doctors in the test g…
Sponsor: MSPU des 3 Provinces • Aim: Diagnosis
Last updated Jun 27, 2026 13:04 UTC
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New algorithm could spare cancer patients unnecessary CT scans for blood clots
Diagnosis CompletedThis study tested whether a simple checklist and blood test (the YEARS algorithm) can safely rule out pulmonary embolism (a blood clot in the lungs) in people with active cancer, compared to the standard approach of doing a CT scan on everyone. About 700 cancer patients with susp…
Sponsor: Leiden University Medical Center • Aim: Diagnosis
Last updated Jun 27, 2026 08:06 UTC
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Blood test aims to catch lung cancer earlier in smokers
Diagnosis CompletedThis study tested whether giving doctors access to a blood test called FirstLook increases lung cancer screening rates among people at high risk. The test looks for DNA fragments in the blood that may signal lung cancer. Researchers compared screening rates in practices that coul…
Sponsor: Delfi Diagnostics Inc. • Aim: Diagnosis
Last updated Jun 27, 2026 07:59 UTC
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Handwashing lessons keep kids in school, study finds
Prevention CompletedThis study tested whether teaching hand and respiratory hygiene to primary school children could lower how often they get sick and miss school. Over 800 students in Erbil, Iraq, took part. Some schools got hygiene lessons and reminders, while others did not. The goal was to see i…
Sponsor: Hawler Medical University • Aim: Prevention
Last updated Jun 27, 2026 11:00 UTC
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New allergy vaccine could end spring sniffles
Symptom relief CompletedThis study tests a new treatment called GNR-127 for people with seasonal allergies to birch pollen. The treatment is a protein that aims to reduce allergy symptoms like sneezing, runny nose, and itchy eyes. The trial involves 150 adults and will check for safety and how well it w…
Phase 1/2 • Sponsor: AO GENERIUM • Aim: Symptom relief
Last updated Sep 21, 2026 18:00 UTC
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New asthma inhaler shows promise in early trial
Symptom relief CompletedThis study tested a single dose of a new albuterol inhaler called PT007 in 118 adults with asthma. Researchers compared how well it opened airways and its safety against a placebo inhaler and the standard Ventolin inhaler. The goal is to see if PT007 works as a quick-relief treat…
Phase 2 • Sponsor: AstraZeneca • Aim: Symptom relief
Last updated Aug 29, 2026 00:00 UTC
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New pill aims to silence chronic cough that Won't quit
Symptom relief CompletedThis study tests an experimental drug called BLU-5937 (camlipixant) in adults with refractory chronic cough, including unexplained chronic cough, that has lasted at least a year. Participants take the drug or a placebo daily for 52 weeks to see if it reduces coughing frequency an…
Phase 3 • Sponsor: Bellus Health Inc. - a GSK company • Aim: Symptom relief
Last updated Jul 16, 2026 00:00 UTC
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Catheter or surgery? new study seeks best way to ease breathing in cancer patients
Symptom relief CompletedThis study looked at 158 adults with cancer who had fluid buildup around their lungs, making it hard to breathe. It compared two treatments: a long-term catheter placed under the skin to drain fluid at home, versus keyhole surgery to remove fluid and seal the space. The goal was …
Sponsor: The University of Western Australia • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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New breathing therapy shows promise for Long-COVID breathlessness
Symptom relief CompletedThis study tested a therapy called Cognitive Muscular Therapy (CMT) for people with Long-COVID who have trouble breathing. CMT combines breathing retraining with techniques to reduce overactive muscles that can interfere with breathing. 18 adults with moderate to severe breathles…
Sponsor: University of Salford • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Simple breathing exercises may ease long COVID breathlessness
Symptom relief CompletedThis study tested a breathing exercise program for people with long COVID who still feel short of breath. 40 adults took part to see if the exercises could improve their breathing and daily activities compared to usual care. The goal was to find a simple way to help manage this c…
Sponsor: University of Nottingham • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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New inhaled drug shows promise for easing lung pressure in rare Heart-Lung condition
Symptom relief CompletedThis study tested an inhaled medication called RT234 in 14 adults with pulmonary arterial hypertension (PAH), a condition where blood pressure in the lungs is dangerously high. The goal was to see if the drug could quickly lower lung blood pressure during a heart catheterization …
Phase 2 • Sponsor: Respira Therapeutics, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 12:04 UTC
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Buzzy® and HSTT take the sting out of kids' injections
Symptom relief CompletedThis study looked at whether two simple, low-cost tools—Buzzy® (a vibrating device) and HSTT (a quick injection technique)—can reduce pain and fear in children aged 4 to 6 during intramuscular shots in the emergency department. 120 children participated, and researchers measured …
Sponsor: Sakarya University • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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Could a tiny dose of muscle relaxant make lung scopes safer?
Symptom relief CompletedThis study looked at whether giving a low dose of a muscle relaxant (rocuronium) during bronchoscopy—a procedure where a tube is inserted into the lungs—could reduce complications like throat spasms and coughing. 153 adults having elective bronchoscopy were split into two groups:…
Sponsor: Harbin Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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Nerve block may fix COVID smell problems, study says
Symptom relief CompletedThis study tested whether a stellate ganglion block (an injection near nerves in the neck) can improve distorted sense of smell (parosmia) caused by COVID-19. 48 adults with long-term smell issues after COVID took part. Half received the nerve block, half got a placebo (saline). …
Phase 2 • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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Zapping away COVID lungs: radiofrequency eases breathlessness
Symptom relief CompletedThis study tested a special type of radiofrequency (448 kHz) combined with manual techniques to help people with ongoing breathing issues after COVID-19. 96 adults who had COVID and still had cough, shortness of breath, or fatigue for over a month received the treatment. The goal…
Sponsor: Clinica Gema Leon • Aim: Symptom relief
Last updated Jun 26, 2026 19:09 UTC
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Can NAC help you cough up mucus faster? new trial results are in
Symptom relief CompletedThis phase 3 trial tested whether the drug N-acetylcysteine (NAC) can thin mucus and make it easier to cough up in adults with respiratory infections like bronchitis or bronchiectasis. About 333 hospitalized patients in China received either NAC, another expectorant (ambroxol), o…
Phase 3 • Sponsor: Zambon SpA • Aim: Symptom relief
Last updated Jun 26, 2026 13:33 UTC
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Researchers dive deep into mysterious lung disease
Knowledge-focused CompletedThis study looked at 275 adults with a lung condition called bronchiectasis, where airways are stretched and trap mucus, leading to infections. The goal was to learn more about the physical traits, lung scans, and germs in the lungs of people with the unexplained form of the dise…
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Jul 30, 2026 00:00 UTC
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New ibuzatrelvir tablet put to the test in healthy volunteers
Knowledge-focused CompletedThis early-stage study is testing a new tablet version of the COVID-19 drug ibuzatrelvir in 18 healthy adults. Researchers want to see how much of the drug gets into the blood when taken as a whole tablet, dispersed in water, or with food. The goal is to compare the new tablet to…
Phase 1 • Sponsor: Pfizer • Aim: Knowledge-focused
Last updated Jul 30, 2026 00:00 UTC
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Tiny lungs, big questions: can we tell which preemies benefit from water pills?
Knowledge-focused CompletedThis study looked at a new method to find out if diuretics (water pills) help individual premature babies with a chronic lung condition called bronchopulmonary dysplasia (BPD). Researchers enrolled 19 very premature infants and used a special 'N-of-1' approach, where each baby wa…
Phase 4 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Knowledge-focused
Last updated Jul 16, 2026 00:00 UTC
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Flute Players' lungs under the microscope: new study eyes Kids' chest mobility
Knowledge-focused CompletedThis observational study will look at 80 children aged 8-14 to see if regularly playing wind instruments like the flute or melodica changes their chest movement, posture, breathing rate, and physical capacity. Half the kids will be wind instrument players, and the other half will…
Sponsor: Yeditepe University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Sleepless night worsens COPD breathing? new study investigates
Knowledge-focused CompletedThis study looked at how one night of no sleep affects shortness of breath and exercise ability in 20 people with COPD. Participants did exercise tests after a normal night and after a sleepless night to compare. The goal was to understand if sleep loss makes breathing harder dur…
Sponsor: Skane University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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London's low emission zone linked to healthier lungs in children
Knowledge-focused CompletedThis study looked at whether London's Ultra Low Emission Zone (ULEZ) — which charges polluting vehicles — improves children's lung health. Researchers tracked lung function in over 3,300 children from schools inside and outside the zone over 4 years. They also measured air pollut…
Sponsor: Queen Mary University of London • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Could a stroll beat a sprint for oxygen testing?
Knowledge-focused CompletedThis study looked at 93 people with lung disease who get short of breath when active. Participants did two 6-minute walk tests: one at their fastest pace and one at their normal walking speed. The goal was to see if the normal-speed test gives a more accurate picture of when they…
Sponsor: Hampshire Hospitals NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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Scientists create a High-Resolution map of the human airways
Knowledge-focused CompletedThis study aims to create a detailed map of the cells lining the airways in healthy people. By analyzing gene activity in individual cells from different parts of the respiratory tract, researchers hope to better understand how these cells interact and how diseases like asthma de…
Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Oximeter showdown: which device gives the best oxygen reading?
Knowledge-focused CompletedThis study tested three different oximeters (Masimo, Nellcor, Nonin) at various oxygen targets in 40 patients with and without COPD. The goal was to see how the choice of oximeter and target affects the amount of oxygen needed. Results could help guide safer oxygen therapy.
Sponsor: Laval University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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CF Patients' COVID antibodies tracked in Two-Year study
Knowledge-focused CompletedThis study looked at whether people with cystic fibrosis (CF) have COVID-19 antibodies from infection or vaccination. Researchers followed 152 adults and children with CF for two years, taking blood samples every six months. They aimed to understand how many had antibodies, how l…
Sponsor: Medical University Innsbruck • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Brain waves may predict ventilator weaning success
Knowledge-focused CompletedThis study looked at whether measuring tiny brain signals during a breathing test can help predict if a patient on a ventilator will successfully breathe on their own. Researchers monitored 70 intubated adults as they tried breathing without the machine. The goal is to find a sim…
Sponsor: Poitiers University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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New breathing monitor could help doctors spot lung trouble faster
Knowledge-focused CompletedThis study tested whether a device called MYOTRACE, which measures how hard a person's breathing muscles are working, can help doctors assess patients with respiratory diseases. 56 adults with conditions like COPD or asthma were included. The goal was to see if the device's readi…
Sponsor: Philips Clinical & Medical Affairs Global • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Study reveals hidden breathing issues in severe MS patients
Knowledge-focused CompletedThis study looked at breathing problems in 70 people with severe multiple sclerosis (MS). Participants had sleep and lung tests to check for breathing muscle weakness. The goal was to better understand how MS affects breathing, not to test a new treatment.
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Study reveals hidden impact of breathing disorder on obese Patients' daily life
Knowledge-focused CompletedThis completed study from Istanbul University looked at 64 obese adults to see if obesity hypoventilation syndrome (OHS) causes extra problems beyond obesity alone. Researchers measured exercise capacity, muscle strength, sleep quality, and quality of life. The goal was to unders…
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Inhaled ED drug tested for safety in healthy people
Knowledge-focused CompletedThis early-phase trial tested the safety and how the body processes an inhaled form of vardenafil (RT234) in 31 healthy adults. Participants received single and multiple doses of the drug via an inhaler or as a pill. The study is complete and focused on side effects and drug leve…
Phase 1 • Sponsor: Respira Therapeutics, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Small study tests tiny adjustments to sleep apnea device
Knowledge-focused CompletedThis study looked at how moving an oral appliance forward by just one millimeter at a time affects sleep apnea severity and symptoms like daytime sleepiness. Twenty adults with moderate or severe sleep apnea took part. Researchers measured breathing pauses during sleep and used q…
Sponsor: Centre Hospitalier de Valence • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:26 UTC