Simple blood test could slash antibiotic overuse for coughs and colds
NCT ID NCT07632651
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether giving general practitioners a rapid C-reactive protein (CRP) test helps them decide when antibiotics are truly needed for patients with respiratory infections. 140 patients with symptoms like cough, fever, or sore throat took part. Doctors in the test group used the Quick read GO device to measure CRP levels, while the control group did not. The goal was to see if the test lowers antibiotic prescribing rates without harming patient care.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Quick read GO CRP test (diagnostic device)
- What this could lead to
- If successful, this approach could help doctors avoid unnecessary antibiotics for respiratory infections, reducing antibiotic resistance.
- What could go wrong
- This is a small, completed pragmatic trial with 140 participants. Results may not apply broadly, and the test's impact on actual health outcomes (not just prescribing) is not assessed.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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140 people
The number who actually took part.
- Started
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Mar 2023
- Finished
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Aug 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients who have received information and given written consent * Patients of any age consulting a general practice with one or more of the following symptoms: fever, cough, arthralgias, myalgias, rhinorrhea; * Symptomatology evolving for more than 24 hours; * Symptoms associated with an upper respiratory tract infection such as otitis, angina, laryngitis, rhinopharyngitis, sinusitis; and/or a lower respiratory tract infection such as acute bronchitis, pneumonia, exacerbation of COPD (chronic obstructive pulmonary disease). Exclusion Criteria: These criteria correspond to factors making interpretation of the CRP value difficult: * Antibiotics taken in the 15 days prior to inclusion * Presence of one of the following signs of severity requiring immediate hospitalization: Impairment of higher functions (altered consciousness) Sign of severity (Pas\<90mmHg; HR\>120/min; FR\>30 cycles/min) Temperature \<35 or \>40°c Inhalation pneumonitis * Sepsis: organ dysfunction, FR\>22cycles/min, PAS≤100 mmHg and Galsgow score ≤ 13(34) * Immediate hospitalization * Pregnancy * Burns * Heat stroke * Presenting with an associated serious pathology: * Associated neoplastic disease in progress * Severe liver failure * Ischemic or thromboembolic pathology * Traumatic pathology * Inflammatory rheumatism * Autoimmune disease
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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MSPU des 3 provinces
Champlitte, Franche-Comté, 70600, France
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