West China Hospital

This study compares two treatment approaches for people with operable head and neck squamous cell carcinoma. One group receives low-dose radiotherapy plus targeted therapy and immunotherapy before surgery, while the other gets only targeted therapy and immunotherapy. The goal is …

This study tested a new way to reconnect the stomach and small intestine after removing the lower part of the stomach in people with advanced stomach cancer. The goal was to see if the new stapling method was safe and worked well. One hundred patients took part, and the researche…

This study looked at whether two diabetes drugs, metformin and empagliflozin, can safely improve metabolic problems (like unhealthy fat buildup and blood sugar issues) in people who have had a kidney transplant. 105 kidney transplant recipients with good kidney function were rand…

This study tested whether a nurse-led safety program using checklists can reduce complications in patients undergoing emergency surgery for a brain bleed (subarachnoid hemorrhage). 156 adults were randomly assigned to receive either standard nursing care or standard care plus the…

This early-phase study tested a combination of low-dose radiation, an immunotherapy drug (tislelizumab), and a targeted therapy (afatinib) given before surgery to people with head and neck cancer. The main goal was to find a safe dose and see how well the treatment shrinks tumors…

This study analyzes health records from over 2 million adults across five continents to see if GLP-1 receptor agonists (like semaglutide and liraglutide) can lower the risk of developing Alzheimer's disease. It focuses on people aged 40 and older with type 2 diabetes or obesity, …

This study tested whether giving head and neck cancer patients detailed oral hygiene and diet instructions can prevent painful mouth sores caused by radiation. 150 patients were split into two groups: one got standard advice, the other got step-by-step oral care training. Researc…

This completed trial tested whether a nurse-led program of early movement, leg-sleeve squeezes, and blood tests could prevent deep vein thrombosis (DVT) in adults after brain or spine surgery. Over 1,200 participants were randomly assigned to either the nurse-led program or stand…

This study tested a new method called the 'Huaxi Tunnel Technique' to protect the recurrent laryngeal nerve during thyroid surgery. The technique uses a diluted epinephrine solution injected along the nerve to create a protective tunnel, reducing the risk of injury. The trial inv…

This study tested a 12-week nursing program based on the Roy Adaptation Model in 160 adults who developed facial paralysis after surgery for a large acoustic neuroma. The program included education, counseling, and facial exercises, and aimed to reduce anxiety and depression whil…

This study tested a 12-week nursing program based on the Roy Adaptation Model for adults who recently had a colostomy. It aimed to reduce anxiety and depression and improve quality of life compared to standard care. 115 participants were randomly assigned to either the special pr…

This study tested whether a probiotic called Lactobacillus reuteri could prevent or treat severe mouth sores in 160 people with head and neck cancer undergoing radiation therapy. Mouth sores are a painful side effect that can make eating difficult. The researchers measured how ma…

This study tested a new breathing test to decide when to remove breathing tubes in patients with acute hypoxic respiratory failure. The test uses noninvasive ventilation to see if patients can breathe on their own earlier. Researchers hope this approach reduces time on invasive v…

This study enrolled 500 skin cancer patients in China and analyzed over 1.2 million of their social media posts using artificial intelligence. The goal was to see if AI could detect signs of psychological distress and suicidal thoughts. Researchers hope this approach could lead t…

This study looked at how levels of a chemical called CGRP change in the blood during radiation therapy for head and neck cancer. Researchers wanted to see if these changes are linked to how much pain patients feel. A total of 23 patients took part, and the study is now complete.

This completed study from West China Hospital examined tumor tissue from 100 colorectal cancer patients who had already received immunotherapy. Researchers measured levels of a protein called PHGDH to see if it was linked to how well the patients responded to treatment and how lo…

This study looked at medical records of 600 children who had brain tumor surgery to find out which kids might have long-term thinking or memory problems. Researchers used machine learning to create a tool that predicts this risk based on brain scans, tumor details, and treatment …

This study looked back at 450 people who had surgery for a rare type of brain tumor (cerebellar glioma). Researchers wanted to see if where the tumor was located and its genetic makeup could predict how much of the tumor could be safely removed and how long patients lived. The go…

This completed study looked at 44 people with a type of brain tumor called glioma. Researchers used a special MRI scan to see if the swollen brain tissue around the tumor still had working connections. They then took small tissue samples during surgery to check if the scan result…

This study looked at 500 children who had surgery for a rare brain tumor called craniopharyngioma. Researchers used MRI scans to grade how much the tumor damaged a key brain area (the hypothalamus). They found that more damage was linked to higher rates of growth hormone deficien…

This study looked at 800 children with congenital hydrocephalus (fluid buildup in the brain) to see which surgery works best: a shunt (a tube that drains fluid) or an endoscopic third ventriculostomy (ETV, a procedure that creates a new drainage pathway). Researchers used MRI sca…

This completed study looked at 1,200 people with neurocutaneous syndromes (NF1, TSC, SWS, VHL) in Western China. Researchers compared those who received genetic testing, targeted drugs, and coordinated specialist care against those who got standard care. The goal was to see if pr…

This study tested a 12-item checklist used by nurses to predict neurological complications like bleeding or re-blockage after endovascular therapy for stroke or aneurysms. Researchers compared 213 patients who were checked with the list to 213 who received standard care. The goal…

This study tested whether a hybrid curriculum combining virtual reality (VR) simulations with live-streamed neurosurgical procedures could improve medical students' decision-making and interest in neurosurgery. 112 fourth-year students were randomly assigned to either the hybrid …