West China Hospital

This study tested whether two diabetes drugs, metformin and empagliflozin, can safely improve metabolic problems (like fat distribution and blood sugar) in people who had a kidney transplant. 105 adults with stable kidney function took one of the drugs or standard care for 12 mon…

This early-phase study tested a combination of low-dose radiation, an immunotherapy drug (tislelizumab), and a targeted therapy (afatinib) given before surgery to people with head and neck cancer. The main goal was to find a safe dose and see how well the treatment shrinks tumors…

This study tested whether teaching patients about proper oral care can prevent painful mouth sores caused by radiation therapy for head and neck cancer. 150 patients completed the trial. The approach focused on education and hygiene routines to reduce complications.

This study tested whether a nurse-led program—including early movement, leg compression sleeves, and blood tests—could prevent dangerous leg blood clots in adults after brain or spine surgery. Over 1,200 participants were randomly assigned to the program or standard care. The goa…

This study tested a 12-week nursing program based on the Roy Adaptation Model for 115 adults who recently had a colostomy. The program included education, support, and family training to see if it could lower anxiety and depression and improve quality of life compared to standard…

This study tested whether a probiotic called Lactobacillus reuteri can prevent or treat severe mouth sores in 160 patients with head and neck cancer undergoing radiation therapy. Mouth sores are a painful side effect that can make eating difficult. The goal was to see if the prob…

This study tested whether a 12-week nursing program based on the Roy Adaptation Model (RAM) could improve anxiety, depression, and quality of life in 160 adults who developed facial paralysis after surgery for a giant acoustic neuroma. Participants received either the RAM program…

This study looked at 800 children with congenital hydrocephalus (fluid buildup in the brain) to see which of two surgeries works better in the long run. Researchers compared a shunt (a tube that drains fluid) with a less invasive procedure called ETV. They also tested if a comput…

This study tested whether a nurse-led safety program (HFMEA) could reduce problems like re-bleeding, infection, or seizures after emergency brain aneurysm surgery. 156 adults with sudden brain bleeds were randomly assigned to either standard nursing care or standard care plus the…

This study looked back at 450 people who had surgery for a type of brain tumor called cerebellar glioma. Researchers wanted to see if where the tumor was located and its genetic makeup could predict how well surgery worked and how long patients lived. The goal was to find better …

This study tested a 12-item checklist that nurses can use to quickly spot patients at high risk for brain complications like bleeding or swelling after endovascular therapy for stroke or aneurysms. Researchers compared 213 patients who were monitored with the checklist to 213 who…

This study followed 1,200 people with neurocutaneous syndromes (like NF1, TSC, and Sturge-Weber) over 20 years to see if genetic testing and targeted drugs improve survival, seizure control, and quality of life. Researchers compared those who received precision medicine (genetic …

This study looked at 500 children who had surgery for a rare brain tumor called craniopharyngioma. Researchers wanted to see if the amount of damage to a key brain area (the hypothalamus) seen on MRI scans could predict future growth hormone problems and thinking or emotional dif…

This study looked at medical records and brain scans from 600 children who had surgery for a brain tumor. The goal was to create a tool that can predict which children might have long-term thinking or memory problems after surgery. Researchers used machine learning to find key ri…

This study looked at 100 colorectal cancer patients who had already received immunotherapy. Researchers measured a protein called PHGDH in their tumor samples to see if it was linked to how well the treatment worked and how long patients lived. The goal was to find a new way to p…

This study measured levels of a protein called CGRP in the blood of 23 people with head and neck cancer during their radiation treatment. The goal was to see if changes in CGRP are linked to pain caused by radiation. The results could help doctors better understand and manage tre…

This study tested a new teaching method for fourth-year medical students. Instead of just watching videos and reading, half the students used virtual reality (VR) to practice brain anatomy and watched live-streamed surgeries with a chance to ask questions. The goal was to see if …

This study looked at 44 people with a type of brain tumor called glioma. Researchers used a special brain scan (fMRI) to see if the swollen tissue around the tumor still worked. They then took small tissue samples during surgery to check if the scan results matched what was seen …