Experimental mRNA injection takes on tough cancers

NCT ID NCT07040943

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial tests a new mRNA-based drug called IL-22BP in 6 adults with advanced solid tumors that have not responded to standard treatments. The drug is injected directly into tumors to see if it is safe and can shrink cancer. The study focuses on safety and tumor response, not a cure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

IL-22BP mRNA injection

What this could lead to

If it works, this could point toward a new treatment option for patients with hard-to-treat solid tumors that have not responded to standard therapies.

What could go wrong

This is a very early Phase 1 trial with only 6 participants, so it is too small to prove effectiveness. The main goal is safety, and there is no guarantee the treatment will shrink tumors or work for others.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

refractory malignant neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Radiation Oncology

    RECRUITING

    Chengdu, Sichuan, 610000, China

    Contact

  • West China Hospital of Sichuan University

    RECRUITING

    Chengdu, Sichuan, 610000, China

    Contact