MRNA vaccine aims to prevent shingles in older adults

NCT ID NCT07400003

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a new mRNA vaccine to prevent shingles (herpes zoster) in adults aged 40 and older. The vaccine uses mRNA technology, similar to some COVID-19 vaccines, and is freeze-dried for easier storage. Researchers will compare different doses against existing vaccines and a placebo to see which is safest and most effective at triggering immunity.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Lyophilized herpes zoster virus mRNA vaccine

What this could lead to

If successful, this could lead to a new, more effective shingles vaccine that is easier to store and transport.

What could go wrong

This is an early phase 1/2 trial, so safety and effectiveness are not yet proven. The vaccine may cause side effects or fail to generate a strong immune response.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

herpes zoster prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Xinjiang Uygur Autonomous Region Center for Disease Control and Prevention

    RECRUITING

    Xinjiang, 831100, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••