HERPES ZOSTER

This study is testing a new, freeze-dried mRNA vaccine designed to prevent shingles (herpes zoster). Researchers are enrolling 519 healthy adults aged 40 and older to evaluate the vaccine's safety and how well it triggers an immune response. The trial will compare different doses…

This study is testing a new vaccine designed to prevent shingles (herpes zoster) in children and teenagers who have had a kidney transplant. These young patients have weakened immune systems from their transplant medications, making them more likely to get shingles. Researchers a…

This study is testing a new investigational shingles vaccine called Z-1018. It will compare the safety and how well it triggers the immune system against the currently approved Shingrix vaccine. The trial will enroll about 764 healthy adults aged 50 and older to find the right do…

This study is testing how well the Shingrix shingles vaccine works and how safe it is for people with HIV. Researchers will compare the immune response in people with HIV to that of healthy volunteers. Participants will receive two vaccine shots over two months and be followed fo…

This study is comparing two antiviral medications, Brivudine and Famciclovir, to see which one works better for treating shingles. It will involve 140 adults with active shingles and will measure how well each drug reduces pain and helps the rash heal. The main goal is to see whi…

This study is testing if the oral medication venlafaxine can prevent postherpetic neuralgia—the severe, long-lasting nerve pain that sometimes follows a shingles outbreak. It will enroll 832 adults who have developed a shingles rash within the last 30 days and are experiencing mo…

This study is testing whether a common muscle relaxant called baclofen can help reduce the often-severe pain caused by shingles. Researchers want to see if adding baclofen to standard pain treatments provides better relief for 750 adults with recent shingles outbreaks. The main g…

This study is testing a medicated skin patch to relieve the pain caused by shingles (herpes zoster). Researchers want to see if applying the patch directly to the painful area can reduce discomfort and improve sleep and daily life for patients. The goal is to offer a localized tr…

This study is testing if a pill called tulodesvenlafaxine can safely reduce the severe pain caused by shingles. It will involve 750 adults who have had a shingles rash for less than 90 days and are still in significant pain. The goal is to see if this medication, which works on b…

This study is testing if adding a new pain medication called Crisugabalin to standard shingles treatment provides better pain relief. It will involve 750 adults with active shingles and moderate to severe pain. Researchers want to see if this newer drug works better and causes fe…

This study compares two existing pain treatments for people with postherpetic neuralgia, the severe nerve pain that can linger after shingles. Researchers are observing 50 patients who have already received either an ultrasound-guided nerve block injection or a radiofrequency the…

This study is testing whether adding a newer pain medication called mirogabalin to standard shingles treatment provides better pain relief. It will involve 750 adults who have had a shingles rash for less than 90 days and are experiencing moderate to severe pain. Researchers will…

This study is testing a medicated skin patch to relieve the pain caused by shingles (herpes zoster). Researchers want to see if applying the patch directly to the painful area can reduce pain severity and improve sleep and daily life for patients. The goal is to offer a localized…

This study is testing if a medication called desvenlafaxine can help reduce the severe pain caused by shingles. Researchers want to see if it works better than current pain treatments and is safe for patients. The trial will involve 750 adults who have had a shingles rash for les…

This small study aims to understand if adding electroacupuncture to standard medication changes how the immune system responds to shingles. Researchers will compare blood samples from 8 female shingles patients, some receiving just medication and others receiving medication plus …