Antidepressant could ease shingles pain

NCT ID NCT07370389

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether adding the antidepressant tulodesvenlafaxine to standard shingles treatment can better relieve pain. It includes 750 adults with moderate to severe shingles pain. The goal is to see if this drug reduces pain scores more than usual care alone.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
tulodesvenlafaxine
What this could lead to
If it works, this could offer a new, more effective way to manage shingles pain and lower the risk of long-term nerve pain.
What could go wrong
This is an early-stage trial without a phase designation, so results are uncertain. The drug may not provide significant pain relief beyond standard treatments and could cause side effects like nausea or dizziness.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HERPES ZOSTER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beijing Tiantan Hospital, Beijing, Beijing 100070

    RECRUITING

    Beijing, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.