Antidepressant could ease shingles pain

NCT ID NCT07370389

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding the antidepressant tulodesvenlafaxine to standard shingles treatment can better relieve pain. It includes 750 adults with moderate to severe shingles pain. The goal is to see if this drug reduces pain scores more than usual care alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

tulodesvenlafaxine

What this could lead to

If it works, this could offer a new, more effective way to manage shingles pain and lower the risk of long-term nerve pain.

What could go wrong

This is an early-stage trial without a phase designation, so results are uncertain. The drug may not provide significant pain relief beyond standard treatments and could cause side effects like nausea or dizziness.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

herpes zoster Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Tiantan Hospital, Beijing, Beijing 100070

    RECRUITING

    Beijing, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••