Could a muscle relaxant ease shingles pain?

NCT ID NCT07378046

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding the muscle relaxant baclofen to standard shingles treatment can better reduce moderate to severe pain. Researchers will enroll 750 adults with shingles rash for less than 90 days. Participants will receive either baclofen plus usual care or usual care alone, and pain levels will be tracked over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Baclofen

What this could lead to

If it works, this could offer a new, safe option to ease shingles pain and lower the risk of long-term nerve pain.

What could go wrong

This is an early-stage trial without a phase, so results are uncertain. Baclofen may not work better than standard care and can cause side effects like drowsiness or muscle weakness.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

herpes zoster Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Tiantan Hospital, Beijing, Beijing 100070

    RECRUITING

    Beijing, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••