New shingles vaccine trial aims to protect vulnerable kids

NCT ID NCT04006808

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a new shingles vaccine (PED-HZ/su) in children aged 1 to 17 who have had a kidney transplant and have weakened immune systems. The vaccine is given as two shots in the arm. Researchers are checking how safe it is, what side effects occur, and how well it boosts the body's defenses against the shingles virus. The trial involves 184 participants and is currently recruiting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
PED-HZ/su (shingles vaccine candidate)
What this could lead to
If it works, this could provide a safe way to prevent shingles in children with weakened immune systems after a kidney transplant.
What could go wrong
This is an early (Phase 1/2) study with only 184 participants, so results may not apply to all. The vaccine could cause side effects like pain, fever, or rarely, more serious issues.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • GSK Investigational Site

    RECRUITING

    Brussels, 1020, Belgium

  • GSK Investigational Site

    RECRUITING

    Ghent, 9000, Belgium

  • GSK Investigational Site

    RECRUITING

    Leuven, 3000, Belgium

  • GSK Investigational Site

    RECRUITING

    Liège, 4000, Belgium

  • GSK Investigational Site

    RECRUITING

    Bordeaux, 33000, France

  • GSK Investigational Site

    RECRUITING

    Lille, 59000, France

  • GSK Investigational Site

    RECRUITING

    Marseille, 13385, France

  • GSK Investigational Site

    RECRUITING

    Montpellier, 34295, France

  • GSK Investigational Site

    WITHDRAWN

    Nantes, 44093, France

  • GSK Investigational Site

    RECRUITING

    Paris, 75015, France

  • GSK Investigational Site

    RECRUITING

    Paris, 75019, France

  • GSK Investigational Site

    RECRUITING

    Toulouse, 31059, France

  • GSK Investigational Site

    COMPLETED

    Genova, 16147, Italy

  • GSK Investigational Site

    RECRUITING

    Milan, 20122, Italy

  • GSK Investigational Site

    RECRUITING

    Padova, 35128, Italy

  • GSK Investigational Site

    RECRUITING

    Roma, 00165, Italy

  • GSK Investigational Site

    RECRUITING

    Torino, 10126, Italy

  • GSK Investigational Site

    RECRUITING

    Gdansk, 80-952, Poland

  • GSK Investigational Site

    RECRUITING

    BaracaldoVizcaya, 48903, Spain

  • GSK Investigational Site

    COMPLETED

    Espluges de Llobregat, 08950, Spain

  • GSK Investigational Site

    RECRUITING

    HebrOn, 08035, Spain

  • GSK Investigational Site

    RECRUITING

    Madrid, 28007, Spain

  • GSK Investigational Site

    RECRUITING

    Madrid, 28046, Spain

  • GSK Investigational Site

    RECRUITING

    Seville, 41013, Spain

  • GSK Investigational Site

    COMPLETED

    Birmingham, B4 6NH, United Kingdom

  • GSK Investigational Site

    COMPLETED

    Cardiff, CF14 4XW, United Kingdom

  • GSK Investigational Site

    RECRUITING

    Glasgow Strathclyde, G51 4TF, United Kingdom

  • GSK Investigational Site

    RECRUITING

    London, WC1N 3JH, United Kingdom

  • GSK Investigational Site

    RECRUITING

    Manchester, M13 9WL, United Kingdom

  • GSK Investigational Site

    RECRUITING

    Nottingham, NG7 2UH, United Kingdom

  • GSK Investigational Site

    RECRUITING

    Southampton, SO16 6YD, United Kingdom

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