New shingles vaccine trial aims to protect vulnerable kids

NCT ID NCT04006808

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a new shingles vaccine (PED-HZ/su) in children aged 1 to 17 who have had a kidney transplant and have weakened immune systems. The vaccine is given as two shots in the arm. Researchers are checking how safe it is, what side effects occur, and how well it boosts the body's defenses against the shingles virus. The trial involves 184 participants and is currently recruiting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

PED-HZ/su (shingles vaccine candidate)

What this could lead to

If it works, this could provide a safe way to prevent shingles in children with weakened immune systems after a kidney transplant.

What could go wrong

This is an early (Phase 1/2) study with only 184 participants, so results may not apply to all. The vaccine could cause side effects like pain, fever, or rarely, more serious issues.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

herpes zoster prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • GSK Investigational Site

    RECRUITING

    Brussels, 1020, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • GSK Investigational Site

    RECRUITING

    Ghent, 9000, Belgium

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • GSK Investigational Site

    RECRUITING

    Leuven, 3000, Belgium

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • GSK Investigational Site

    RECRUITING

    Liège, 4000, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • GSK Investigational Site

    RECRUITING

    Bordeaux, 33000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • GSK Investigational Site

    RECRUITING

    Lille, 59000, France

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • GSK Investigational Site

    RECRUITING

    Marseille, 13385, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • GSK Investigational Site

    RECRUITING

    Montpellier, 34295, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • GSK Investigational Site

    WITHDRAWN

    Nantes, 44093, France

  • GSK Investigational Site

    RECRUITING

    Paris, 75015, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • GSK Investigational Site

    RECRUITING

    Paris, 75019, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • GSK Investigational Site

    RECRUITING

    Toulouse, 31059, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • GSK Investigational Site

    COMPLETED

    Genova, 16147, Italy

  • GSK Investigational Site

    RECRUITING

    Milan, 20122, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • GSK Investigational Site

    RECRUITING

    Padova, 35128, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • GSK Investigational Site

    RECRUITING

    Roma, 00165, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • GSK Investigational Site

    RECRUITING

    Torino, 10126, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • GSK Investigational Site

    RECRUITING

    Gdansk, 80-952, Poland

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • GSK Investigational Site

    RECRUITING

    BaracaldoVizcaya, 48903, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • GSK Investigational Site

    COMPLETED

    Espluges de Llobregat, 08950, Spain

  • GSK Investigational Site

    RECRUITING

    HebrOn, 08035, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • GSK Investigational Site

    RECRUITING

    Madrid, 28007, Spain

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • GSK Investigational Site

    RECRUITING

    Madrid, 28046, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • GSK Investigational Site

    RECRUITING

    Seville, 41013, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • GSK Investigational Site

    COMPLETED

    Birmingham, B4 6NH, United Kingdom

  • GSK Investigational Site

    COMPLETED

    Cardiff, CF14 4XW, United Kingdom

  • GSK Investigational Site

    RECRUITING

    Glasgow Strathclyde, G51 4TF, United Kingdom

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • GSK Investigational Site

    RECRUITING

    London, WC1N 3JH, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • GSK Investigational Site

    RECRUITING

    Manchester, M13 9WL, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • GSK Investigational Site

    RECRUITING

    Nottingham, NG7 2UH, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • GSK Investigational Site

    RECRUITING

    Southampton, SO16 6YD, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••