Brain scan grading predicts growth problems in child tumor survivors

NCT ID NCT07342686

Completed Knowledge-focused Sponsor: West China Hospital Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at 500 children who had surgery for a rare brain tumor called craniopharyngioma. Researchers used MRI scans to grade how much the tumor damaged a key brain area (the hypothalamus). They found that more damage was linked to higher rates of growth hormone deficiency and thinking or emotional problems. The goal is to help doctors create better care plans for each child based on their individual risk.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could help doctors predict which children need closer monitoring for growth and brain health after brain tumor surgery.
What could go wrong: This is an observational study, not a treatment trial. It cannot prove cause and effect, and results may not apply to all patients or hospitals.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

craniopharyngioma isolated congenital growth hormone deficiency pituitary dwarfism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CRANIOPHARYNGIOMA GROWTH HORMONE DEFICIENCY (GHD)

Contacts and locations

Locations

West China Hospital of Sichuan University

Chengdu, Sichuan, China

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