West China Hospital

This study tests a combination of three treatments—immunotherapy (tislelizumab), targeted therapy (afatinib), and a modified herpes virus (lysogenic HSV)—given before surgery for head and neck squamous cell carcinoma. The goal is to see if this approach safely shrinks tumors and …

This phase II trial tests a combination of two drugs (anlotinib and cadonilimab) plus a special type of radiation (PULSAR) in 26 people with advanced bile duct cancer that has worsened after standard treatment. The goal is to see if this triple therapy can shrink tumors and contr…

This early-phase trial is testing whether two drugs, HRS-4642 and nimotuzumab, can safely shrink tumors in people with recurrent or metastatic pancreatic ductal adenocarcinoma. About 20 patients will receive the combination to find the best dose and see how well it works. The goa…

This early-phase study tests whether adding Akkermansia probiotics to standard immunotherapy and chemotherapy can safely help patients with advanced colorectal cancer that hasn't responded to prior treatments. The trial enrolls 22 adults whose tumors are MSS/pMMR type, which typi…

This early-phase trial tests whether combining two drugs—camrelizumab (an immunotherapy) and palbociclib (a targeted therapy)—is safe and feasible when given before surgery for esophageal cancer. Six adults with resectable esophageal squamous cell carcinoma will receive the drugs…

This early-stage trial tests a single dose of a gene therapy called JWK007 in 3 boys aged 5-10 with Duchenne muscular dystrophy. The main goal is to check safety and tolerability, while also looking at whether it helps muscle function. It is a very small, first-in-human study, so…

This early-stage study tests a new immune-based treatment for people with advanced cancers linked to the Epstein-Barr virus (EBV) who have not responded to standard therapies. Only 6 participants are enrolled to check if the treatment is safe and to get a first look at whether it…

This study was designed to see if adding low-dose radiotherapy to a combination of targeted therapy (Afatinib) and immunotherapy (Tislelizumab) before surgery could improve outcomes for people with resectable head and neck cancer. The trial was withdrawn before enrolling any part…

This study tests whether a superoxide dismutase (SOD) spray can prevent severe radiation dermatitis (skin burns) in 140 head and neck cancer patients undergoing radiotherapy. The spray aims to neutralize free radicals that cause skin damage. If effective, it could reduce treatmen…

This study tests whether a superoxide dismutase (SOD) spray can prevent severe radiation dermatitis (skin burns) in 140 head and neck cancer patients undergoing radiotherapy. The spray aims to neutralize free radicals that cause skin damage. Researchers will check patients weekly…

This study tests whether a spray made from spirulina (a type of algae) can prevent or reduce severe mouth sores in people receiving radiation for head and neck cancer. About 70 patients will use either the spirulina spray or a placebo spray during their radiotherapy. The goal is …

This study follows 20,000 healthy Chinese adults aged 40-75 living at various altitudes to see if chronic low oxygen levels increase the risk of multiple system atrophy (MSA), a rare and fatal brain disease. Participants undergo checkups and overnight oxygen monitoring, then are …

This study looks at 500 people with advanced neuroendocrine tumors to see if starting with surufatinib or somatostatin analogs leads to better outcomes. Researchers will compare how long the cancer is controlled with each sequence. The goal is to provide real-world evidence to gu…

This study looks at why some women develop hard scar tissue (capsular contracture) around breast implants after mastectomy for breast cancer. Researchers will follow 300 women who had immediate implant-based reconstruction and check their results six months later. The goal is to …

This study tests whether a gamified teaching method—using team challenges, points, and digital badges—helps neurology residents learn and remember more than traditional lectures. About 240 residents will try both formats, wearing wristbands that track stress and attention. Resear…