Head and neck cancer trial pulled before it even started

NCT ID NCT06804850

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study was designed to see if adding low-dose radiotherapy to a combination of targeted therapy (Afatinib) and immunotherapy (Tislelizumab) before surgery could improve outcomes for people with resectable head and neck cancer. The trial was withdrawn before enrolling any participants, so no data were collected.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Tislelizumab (immunotherapy), Afatinib (targeted therapy), and low-dose radiotherapy

What this could lead to

If it had worked, this could have pointed toward a more effective pre-surgery treatment for head and neck cancer, potentially improving tumor shrinkage before surgery.

What could go wrong

The trial was withdrawn before any participants were enrolled, so no results are available. It is unknown whether the combination would have been safe or effective.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

head and neck cancer Head and Neck Neoplasms head and neck squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.