University Of Pennsylvania

This study tested whether kidneys from donors with hepatitis C can be safely transplanted into people without the virus. After transplant, patients received antiviral medication to cure the hepatitis C infection. The goal was to expand the number of available kidneys for people w…

This study tested whether a fast breast MRI can detect cancers that mammograms miss in women who had breast-conserving therapy for breast cancer at least three years earlier. About 184 women with a recent negative mammogram and no symptoms received a quick MRI. The goal was to se…

This study tested a non-invasive brain stimulation technique called tDCS combined with language therapy in 76 adults with primary progressive aphasia (PPA), a condition that slowly destroys language abilities. Participants received either real or fake stimulation over 10 sessions…

This study tested whether simple, affordable robots can help people who have had a stroke improve arm and hand function. 27 older adults (55+) who were at least 3 months post-stroke used the Rehab CARES system in a community setting. They performed exercises with force-feedback r…

This study tested whether a dye called indocyanine green can make brain and spinal cord tumors glow during surgery, helping surgeons see and remove them more completely. About 363 adults with brain tumors received the dye before surgery, and special cameras were used to detect th…

This study looked at whether asking people to "opt in" or "opt out" of a clinical trial changes how many people with peripheral artery disease (PAD) actually join. Over 5,000 adults with PAD were contacted by email. The goal was to see which approach leads to more enrollment and …

This small study looked at whether taking aspirin can block the uncomfortable flushing (redness and warmth) that niacin causes. Nine healthy adults took either aspirin or a placebo for five days, then a dose of niacin. Researchers measured flushing-related chemicals in their bloo…

This study tested a smartphone app called SMART-HABITS in 47 adults with chronic kidney disease and high blood pressure. The app provided reminders, feedback, and educational resources to help patients track their blood pressure and steps. The goal was to see if patients would us…

This study looked at over 634,000 Medicaid enrollees aged 15 and older to figure out who is most likely to have a stimulant overdose and when that risk is highest. Researchers used medical records from 2016-2020 to build models that predict overdose risk based on personal and nei…

This study looked at whether chemicals in the blood (metabolomics) can help diagnose obstructive sleep apnea and show how well treatment is working. Researchers studied 388 adults with and without sleep apnea. They collected blood samples and tracked how using a CPAP machine affe…