Should patients with rare vasculitis stay on Low-Dose steroids? trial seeks answer

NCT ID NCT01940094

First seen Apr 02, 2026 · Last updated May 15, 2026 · Updated 5 times

Summary

This study looked at 159 adults with granulomatosis with polyangiitis (GPA), a rare disease causing blood vessel inflammation. Participants were randomly assigned to either keep taking a low dose of prednisone (5 mg/day) or stop it completely for about six months. The goal was to see which approach better prevents disease flares without causing too many side effects.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02215, United States

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Mount Sinai Hospital

    Toronto, Ontario, M5T 3L9, Canada

  • St. Joseph's Healthcare

    Hamilton, Ontario, Canada

  • University of Kansas Medical Center

    Kansas City, Kansas, 66160, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • University of Pittsburgh

    Pittsburgh, Pennsylvania, 15261, United States

  • University of Utah

    Salt Lake City, Utah, 84112, United States

Conditions

Explore the condition pages connected to this study.