Experimental liquid drug tested in ventilator patients with rare lung bleeding disease
NCT ID NCT07556484
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early study tests whether a liquid form of the drug avacopan can be safely given through a feeding tube to critically ill patients with ANCA vasculitis who have severe lung bleeding and need a ventilator. The main goal is to measure how the drug levels change in the blood over 72 hours. Only 6 participants will be enrolled at Mayo Clinic.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
avacopan (Tavneos)
What this could lead to
If it works, this could point toward a way to give avacopan to very sick patients who cannot swallow pills, potentially helping control severe lung inflammation.
What could go wrong
This is a tiny, early-phase study with only 6 participants, so results may not apply broadly. The drug is given in an experimental liquid form, and its safety and effectiveness in this setting are not yet known.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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Mayo Clinic in Rochester
RECRUITINGRochester, Minnesota, 55905, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact