Tiny study probes why islet transplants shield against low blood sugar

NCT ID NCT03079921

First seen May 12, 2026 · Last updated May 24, 2026 · Updated 4 times

Summary

This early-phase study looked at how the nervous system helps control blood sugar in people with type 1 diabetes who received islet cell transplants. Nine participants received drugs that block certain nerve signals to see how their transplanted cells responded to low blood sugar. The goal was to understand why these transplants can protect against dangerous low blood sugar episodes, not to test a new treatment.

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Contacts and locations

Locations

  • University of Pennsylvania - Institute for Diabetes, Obesity and Metabolism

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.