Brain scans reveal hidden impact of opioid overdoses

NCT ID NCT05651516

First seen Jan 11, 2026 · Last updated Jun 10, 2026 · Updated 28 times

Summary

This study looked at whether opioid use disorder and non-fatal overdoses cause a harmful protein called tau to build up in the brain. Researchers used special PET/CT scans on 12 adults, including those with opioid use disorder and healthy volunteers. The goal was to understand long-term brain changes, not to test a treatment.

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Contacts and locations

Locations

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.