University Of North Carolina, Chapel Hill

This study tested whether a program that combines job search support with health coaching can reduce chronic disease risks in unemployed adults. About 455 people receiving employment services took part. Researchers measured changes in stress, weight, and blood pressure over 12 mo…

This study looked at whether sildenafil is safe for premature babies born before 29 weeks who are at risk of a serious lung condition called bronchopulmonary dysplasia. 109 babies on breathing support were given the drug, and researchers tracked side effects and how the drug move…

This study looked at whether intensive, non-surgical dental treatment (deep cleaning and oral hygiene advice) can improve oral health and also affect markers of heart disease and type 2 diabetes. About 200 adults with gum disease and either heart disease or diabetes (or prediabet…

This study tested a program called Gender-affirming Abriendo Puertas for transgender women living with HIV in Santo Domingo. The program includes counseling, peer support, and community activities to help women take their HIV medication and keep the virus under control. About 120…

This pilot study tested whether a single high dose of vitamin D given shortly after a burn injury can prevent chronic pain. Forty adults took either vitamin D or a placebo and were followed for 6 months. Researchers checked safety, pain levels, and immune system changes. The goal…

This study looked at how to best give daily HIV prevention pills (PrEP) to pregnant women in Sub-Saharan Africa. Researchers tested different doses of the medication in 54 pregnant women to find the dose that provides the best protection against HIV while being safe for both the …

This pilot study tested a counseling program called the Friendship Bench for 106 teens aged 13-18 living with HIV in Malawi. The goal was to see if the program was feasible and acceptable, and whether it could reduce symptoms of depression and anxiety. Participants were split int…

This study looked at whether women who had surgery for prolapse or incontinence could safely remove their urinary catheter at home just one day after surgery, instead of the usual 3-4 days. 128 women who failed a voiding trial before leaving the hospital took part. The goal was t…

This study looked at whether adding an inhaled sugar powder called Bronchitol (mannitol) helps clear mucus from the lungs faster in people with cystic fibrosis who already take the triple-combination drug E/T/I. Fourteen adults with moderate to severe lung disease took part. The …

This study looked at whether a stretching routine could reduce cardiovascular risks in 224 pregnant women with obesity. Participants did stretching or usual moderate/vigorous activity from week 27 to 37 of pregnancy. The goal was to see if stretching improved blood pressure and o…

This study tested whether giving teens with ADHD and their parents a question list or a short video before a doctor visit helps them ask more questions and get better care. About 126 English-speaking teens aged 11-17 with ADHD took part. The goal was to see if these tools improve…

This study tested a special palliative care program for people with late-stage Alzheimer's or related dementias and their family caregivers. The program started during a hospital stay and included dementia-specific care, caregiver education, and help transitioning home. Researche…

This study tested whether a 12-week time-restricted feeding program (eating only during certain hours) is practical and acceptable for older adults (ages 65-80) who have mild cognitive impairment and obesity. Researchers measured changes in memory, thinking skills, and metabolic …

This study looked at 27 people with Primary Ciliary Dyskinesia (PCD), a rare lung disease, to see how different gene mutations affect the lungs' ability to clear mucus. Researchers measured clearance using a safe radioactive tracer and compared results between those with mild and…

This small study looked at whether MRI scans can accurately find brown adipose tissue (BAT) — a type of body fat that burns calories — in healthy adults. Eight volunteers had both MRI and PET scans under mild cold conditions. The goal was to see how well MRI results matched PET, …

This study looked at how different types of exercise affect metabolism in women going through perimenopause. 28 overweight or obese women in early or late perimenopause took part. Researchers compared high-intensity interval training (HIIT) with traditional aerobic exercise and a…

This study looked at ways to help more people with type 2 diabetes attend diabetes self-management education classes. Researchers tested different methods to increase referrals from doctors and used peer support to encourage attendance. The study involved 32 participants and focu…

This study looked at whether a dietary supplement (fiber plus green tea) can make people feel more full from alcohol and change their response to drinking. 64 at-risk drinkers took either the supplement or a placebo before an alcohol challenge. The goal was to see if the suppleme…

This study looked at whether a lab-made version of lactoferrin (a protein found in milk) can help healthy adults better regulate iron, support gut health, and boost immune function. About 92 active adults aged 18-42 took either the supplement, natural lactoferrin, or a placebo da…