Gene clues could unlock milder forms of rare lung disease

NCT ID NCT04901715

First seen Nov 01, 2025 · Last updated May 03, 2026 · Updated 19 times

Summary

This study looked at 27 people with Primary Ciliary Dyskinesia (PCD), a rare lung disease, to see how different gene mutations affect the lungs' ability to clear mucus. Researchers measured clearance using a safe radioactive tracer and compared results between those with mild and severe gene types, as well as healthy volunteers. The goal is to better understand which genes lead to milder disease, which could guide future treatments.

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Contacts and locations

Locations

  • University of North Carolina Chapel Hill

    Chapel Hill, North Carolina, 27514, United States

Conditions

Explore the condition pages connected to this study.