University Of North Carolina, Chapel Hill

This study tests if anifrolumab, a drug that targets inflammation, can reduce symptoms of hidradenitis suppurativa (HS), a chronic skin condition causing painful lumps. About 15 adults with moderate-to-severe HS will receive the drug intravenously over 24 weeks. Researchers will …

This study looks at how well dupilumab, an FDA-approved drug, works for people with severe eosinophilic esophagitis (EoE) who have narrowing of the esophagus. About 23 participants will receive weekly injections of dupilumab for one year. The goal is to see if the drug reduces in…

This study tests a freezing balloon device to remove abnormal cells in the esophagus of people with Barrett's esophagus that did not improve after standard heat treatments. About 70 adults with precancerous changes will receive the freezing treatment and be followed for 12 months…

This study tests whether a brief alcohol intervention (a few counseling sessions) helps people who drink heavily stay on PrEP, the daily pill that prevents HIV. About 562 people starting or restarting PrEP in Hanoi will either get the alcohol counseling or standard care. The goal…

This study tests a program called Thriving Hearts, which offers extra support and connection for pregnant people through local health departments in 10 North Carolina counties. The goal is to see if this program can lower the number of dangerous high blood pressure disorders duri…

This study follows 40 adults aged 55 and older with osteoarthritis who are receiving low-dose radiation as part of their usual care. Researchers will track changes in pain, physical function, and quality of life over time using surveys. The goal is to see if this treatment helps …

This study looks at how to bring a group program that teaches non-drug pain management (like yoga, meditation, and education) to community health centers that serve low-income people. About 70 patients with chronic pain will take part. The goal is to see if training clinic staff …

This study aimed to compare two pain medicines given during spinal anesthesia for cesarean delivery in patients with opioid use disorder who take buprenorphine. It planned to enroll about 0 participants and measure pain scores and recovery. The trial was withdrawn before any part…

This study compares two programs designed to help parents of adolescents and young adults (ages 11-27) with intellectual or developmental disabilities. One program teaches parents advocacy skills, while the other connects them with other parents for peer learning. Researchers wil…

This study looks at whether encouraging young adults (ages 18-29) to have more in-person social interactions with people they don't know well can help reduce feelings of social isolation and loneliness. About 1,900 participants will use a smartphone app for 6 weeks to track their…

This study tests whether an artificial intelligence (AI) tool can help outpatient doctors save time by summarizing medical records. About 150 doctors will either use the tool right away or wait 8 weeks. The goal is to see if the tool reduces workload and burnout without changing …

This study looks at whether teachers in rural primary schools in the Indian Himalayas can be trained to provide mental health support to children with behavior problems. Over 20,000 children, teachers, and parents from 90 schools will take part. The goal is to see if this approac…

This study aimed to see if rhythmic electrical stimulation of the brain could improve working memory in people with drug-resistant epilepsy. Researchers planned to use electrodes already placed in the brain for epilepsy surgery to deliver tiny zaps and measure memory performance.…

This study tests whether a mobile health tool used by community health workers can improve follow-up care for women after cesarean sections in rural Rwanda. About 1,350 women who had a C-section at Kirehe District Hospital will be randomly assigned to either home visits using the…

This study follows 9,000 pregnant women in Zambia from early pregnancy through one year after birth. Researchers collect health information and samples to learn what causes preterm birth, aiming to find new prevention strategies. It is an observational study, not a treatment tria…