Freezing therapy offers new hope for tough Barrett's cases

NCT ID NCT03554356

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests a freezing device (CryoBalloon) to treat Barrett's esophagus that hasn't improved after multiple standard heat treatments. About 70 adults with precancerous changes in the esophagus will receive the freezing therapy. The goal is to safely remove all abnormal tissue and prevent cancer progression.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Barrett esophagus esophagus carcinoma in situ gastric intestinal metaplasia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Columbia University

    New York, New York, 10032, United States

  • Geisinger Clinic

    Danville, Pennsylvania, 17822, United States

  • Georgetown University

    Washington D.C., District of Columbia, 20057, United States

  • Johns Hopkins University

    Baltimore, Maryland, 21205, United States

  • Mayo Clinic Rochester

    Rochester, Minnesota, 55905, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • Northwell Health

    Lake Success, New York, 11042, United States

  • UNC Chapel Hill

    Chapel Hill, North Carolina, 27599, United States

  • UTHealth Science Center/Herman Memorial

    Houston, Texas, 77030, United States

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohio, 44106, United States

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35294, United States