University Of North Carolina, Chapel Hill

This study is testing whether a daily liquid placed under the tongue can help children with cashew allergy become less sensitive to cashews. Researchers will give the treatment or a placebo to 45 children aged 1-11 for 18 months to see if it safely increases the amount of cashew …

This study looks at whether a simple questionnaire given during a dental visit can identify children aged 8-13 who are at risk for sleep-disordered breathing (SDB), including obstructive sleep apnea. Kids will be grouped as low- or high-risk based on the questionnaire, then wear …

This study tests a personalized support program (PTBCARE+) for pregnant individuals at high risk of delivering early. About 1,228 participants will either receive the program—which includes stress reduction tools, a website/app, and massage—or standard prenatal care. The goal is …

This study tests if giving malaria medicine to everyone living with a pregnant woman can help protect her from getting malaria. About 300 people in Uganda will take part. The goal is to see if this approach is practical and acceptable to families.

This study tests whether a special omega-3 supplement can reduce pain in adults with chronic temporomandibular disorder (TMD), a condition causing jaw pain. One hundred participants will take either the supplement or a placebo daily for 8 weeks. The goal is to see if the suppleme…

This study is testing whether a brief, breath-focused therapy called Acceptance and Commitment Therapy (ACT) is practical and safe for adults with chronic cough. Researchers will enroll 30 people to see if they find the program acceptable and easy to follow. The goal is to unders…

This study tests a three-part training program for older adults (65+) with diabetes who use insulin. The program teaches CGM technology, data skills, and lifestyle adjustments to improve glucose monitoring and reduce diabetes-related distress. 150 participants will be compared to…

This study tests whether two mast cell stabilizing drugs, ketotifen and cromolyn, can safely reduce ongoing symptoms like fatigue and brain fog after a tick-borne illness. About 50 adults aged 21-65 who had ehrlichiosis or Rocky Mountain spotted fever in the last 3 years will rec…

This study looks at whether a special training program can help surgeons and hospital staff reduce the number of opioid painkillers they prescribe after surgery. About 40 healthcare workers and patient representatives at hospitals in North Carolina will take part. The goal is to …

This study compares two types of front-of-package labels to see which one better helps Indonesian adults spot and avoid foods high in sugar, salt, or fat. About 1,000 participants will view different labels and answer survey questions. The goal is to find the most effective label…

This study in rural Guatemala tests if a special nutrition program for gut health and a caregiver training class, alone or together, can improve brain development in children. About 400 mothers and their babies will join from pregnancy until the child is 2 years old. The goal is …

This study tests a virtual parenting program called AMP-CARE for parents of teens aged 11-14. Researchers want to see if it helps parents feel more confident and learn more about teen mental health. About 60 parents will take surveys and some will attend the program right away, w…

This study looks at how natural hormone changes during the menstrual cycle impact brain areas linked to mood and irritability in teenage girls at risk for suicide. Fifty girls aged 12-16 will take either a birth control pill to stabilize hormones or a placebo for 8 weeks each, wh…

This study looks at how cartoon characters on food packages and warning labels influence what Colombian children aged 12 to 17 think about ultraprocessed foods. About 1,960 kids will take an online survey to see if characters make warning labels less effective. The goal is to und…