University Of North Carolina, Chapel Hill
Clinical trials sponsored by University Of North Carolina, Chapel Hill, explained in plain language.
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Fish oil and vitamin d may stop chronic pain after burns
Prevention TerminatedThis study tested whether giving fish oil and vitamin D soon after a serious thermal burn could prevent chronic pain. It enrolled 24 adults with burns covering less than 30% of their body. The trial was stopped early, so results are limited, but the goal was to find a safe, low-c…
Phase: PHASE2 • Sponsor: University of North Carolina, Chapel Hill • Aim: Prevention
Last updated May 14, 2026 12:06 UTC
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Mindfulness app aims to ease anxiety in communities hit hard by COVID-19
Symptom relief TerminatedThis study tested a smartphone app called SMILE that teaches mindfulness to help reduce anxiety. It included 398 Black and Latino adults who had moderate anxiety. Participants used the app for 8 weeks and reported their stress levels and heart activity. The goal was to see if the…
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Symptom relief
Last updated May 16, 2026 23:51 UTC
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Can a nasal device boost mood? small study investigates SinuSonic
Symptom relief TerminatedThis study looked at whether using the SinuSonic device for 5 weeks could improve anxiety, depression, and overall well-being in adults with chronic nasal or sinus congestion. Sixteen participants completed surveys about their physical and mental health before and after using the…
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Symptom relief
Last updated May 11, 2026 20:52 UTC
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Blood test may help some ANCA patients skip maintenance drugs
Knowledge-focused TerminatedThis study looked at whether measuring a specific type of immune cell (CD5+ regulatory B cells) in the blood could help doctors decide if ANCA vasculitis patients need ongoing treatment to prevent relapses. The idea was that patients with normal levels of these cells after initia…
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated May 16, 2026 23:51 UTC
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Xenon MRI aims to spot hidden fat that burns calories
Knowledge-focused TerminatedThis early-phase study tested whether a special MRI technique using inhaled xenon gas could detect brown adipose tissue (BAT) in 17 healthy adults. Brown fat helps burn calories, and researchers wanted to see if this imaging method could measure its activity during cold exposure.…
Phase: PHASE1 • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated May 16, 2026 23:49 UTC
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Digital platform for psychosis care: what helps and hinders?
Knowledge-focused TerminatedThis study looked at how well a digital tool called Horyzons works in clinics for people with early psychosis. Researchers talked to doctors and patients to find out what made it easy or hard to use. The goal was to learn how to better bring such tools into regular care.
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated May 16, 2026 23:38 UTC
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Brain injury drug study halted after only 5 patients
Knowledge-focused TerminatedThis small pilot study aimed to see if antiseizure medications change brain connectivity patterns in patients with severe acute brain injuries who are unconscious. Only 5 participants were enrolled before the study was stopped early. The researchers used brain scans to look for s…
Phase: PHASE4 • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated May 12, 2026 13:43 UTC
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Virtual reality training aims to reduce postpartum pain disparities
Knowledge-focused TerminatedThis study tested a virtual reality training program for healthcare teams to improve care for new mothers and reduce pain disparities. About 66 participants, including doctors, nurses, and doulas, took part. The study was ended early, so results are limited.
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated May 11, 2026 20:53 UTC
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Brain zapping study sees if electricity can make you more flexible
Knowledge-focused TerminatedThis small study tested whether a single session of non-invasive brain stimulation (alpha-tACS) could change brain activity and help people be less stuck in their habits. Seven healthy adults, including some with risky drinking histories, completed tasks while receiving real or f…
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated May 07, 2026 18:42 UTC
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Can video coaching help rural pharmacists boost COVID-19 vaccine confidence?
Knowledge-focused TerminatedThis study looked at whether virtual coaching (like video calls) helps rural pharmacists better counsel people who are hesitant about getting the COVID-19 vaccine. Sixteen pharmacies took part, first using standard training and then adding a personal coach. The main goal was to s…
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated May 06, 2026 16:14 UTC