University Of North Carolina, Chapel Hill
Clinical trials sponsored by University Of North Carolina, Chapel Hill, explained in plain language.
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Fish oil and vitamin d tested to stop burn pain before it starts
Prevention TerminatedThis study tested whether giving fish oil and vitamin D soon after a burn injury could prevent chronic pain. It included 24 adults with burns covering less than 30% of their body. The trial was stopped early, so results are limited, but the goal was to find a safe, low-cost way t…
Phase: PHASE2 • Sponsor: University of North Carolina, Chapel Hill • Aim: Prevention
Last updated Jun 27, 2026 12:30 UTC
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Mindfulness app for anxiety in underserved groups fizzles out early
Symptom relief TerminatedThis study tested a smartphone app that teaches mindfulness meditation to help Black and Latino adults with anxiety during the COVID-19 pandemic. About 400 participants were assigned to one of two mindfulness programs or a waitlist. The trial was terminated early, so we don't hav…
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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Can a simple nasal device boost mood and ease congestion?
Symptom relief TerminatedThis study tested whether using the SinuSonic device—a handheld tool that uses sound and gentle pressure to relieve nasal congestion—could also improve anxiety, depression, and overall well-being in adults with chronic stuffy nose. Sixteen participants used the device for 5 weeks…
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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VR training for maternity staff aims to improve care, but study ends early
Knowledge-focused TerminatedThis study tested a virtual reality training program for maternity care providers, nurses, lactation consultants, and doulas. The goal was to improve teamwork and reduce pain disparities for birthing parents. The study enrolled 66 participants but was terminated early, so the res…
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Brain zapping study halted early: could it have helped heavy drinkers think more flexibly?
Knowledge-focused TerminatedThis study tested whether a single session of non-invasive brain stimulation (alpha-tACS) could change brain activity and help people break habits. Researchers compared the stimulation to a fake (sham) version in healthy adults and those with a history of heavy drinking. The stud…
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Rural pharmacists get virtual coaching to tackle vaccine hesitancy
Knowledge-focused TerminatedThis study looked at whether virtual coaching helps rural pharmacists better counsel patients who are hesitant about COVID-19 vaccines. Sixteen pharmacies took part, first receiving standard training and then adding one-on-one video coaching. The main goal was to see if coaching …
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Blood test may help some ANCA patients skip unnecessary drugs
Knowledge-focused TerminatedThis study looked at whether a specific type of immune cell (CD5+ regulatory B cells) can predict relapse risk in people with ANCA vasculitis, a rare autoimmune disease that damages blood vessels. Researchers aimed to see if patients with normal levels of these cells after initia…
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Xenon MRI aims to spot 'Good' fat in obesity fight
Knowledge-focused TerminatedThis early study tested whether a special MRI technique using inhaled xenon gas can detect brown adipose tissue (BAT) in healthy adults. Brown fat burns calories to generate heat, and researchers wanted to see if this imaging method could measure its activity. The study involved …
Phase: PHASE1 • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Tiny study probes how seizure meds affect brain wiring after injury
Knowledge-focused TerminatedThis pilot study aimed to see if antiseizure drugs like phenobarbital and levetiracetam change brain connectivity patterns in people with severe acute brain injury and reduced consciousness. Only 5 participants were enrolled before the study was terminated. Researchers used resti…
Phase: PHASE4 • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Online tool for psychosis support tested in clinics – but study stopped early
Knowledge-focused TerminatedThis study looked at whether a digital platform called Horyzons could be used in clinics that help young people with early psychosis. The platform offers therapy content and a safe social network. Researchers wanted to understand what helps or hinders its use in real-world care. …
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:15 UTC