Fish oil pills tested as new hope for jaw pain sufferers

NCT ID NCT07437313

Not yet recruiting Symptom relief Sponsor: University of North Carolina, Chapel Hill Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a special omega-3 supplement can reduce pain in adults with chronic temporomandibular disorder (TMD), a condition causing jaw pain. One hundred participants will take either the supplement or a placebo daily for 8 weeks. Researchers will measure changes in pain intensity, jaw function, and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: omega-3 supplement enriched with specialized pro-resolving mediator precursors
What this could lead to: If it works, this could offer a natural, low-risk option for managing chronic jaw pain without drugs.
What could go wrong: This is a small, early-phase trial (100 people) testing a supplement, not a drug. Results may not apply to everyone, and the supplement may not reduce pain better than placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

anxiety disorder Facial Pain migraine disorder temporomandibular joint disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TEMPOROMANDIBULAR DISORDER (TMD)

Contacts and locations

Locations

University of North Carolina at Chapel Hill

Chapel Hill, North Carolina, 27599, United States

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